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Respiratory Disorders  (Expert Forum)
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High c02 a feature of (complicated) OSA ??
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High c02 a feature of (complicated) OSA ??

by windsong1602, Sep 16, 2004 12:00AM
My 8 year old son has OSA (AHI 11) and uses a Autopap. His pressure requirements are very high for a child (His 95 percentile goes up to maximum setting of 13cm on his machine yet the doctors tell me 8cm is maximum pressure for a child his age)
Last time we were in hospital one of the Drs said that very high c02 levels like my sons (up to 10kpa) are not normal with just OSA and for him to go so high as soon as he falls asleep (without CPAP) he must have another underlying disorder. He needs high pressure to keep his c02 under control - 02 not a problem. Another doctor disagreed and said high c02 like his was normal with OSA
He has just been diagnosed with asthma - no wheezing just chest pain/tightness and difficulty getting air in feeling. His last 2 chest x-rays have shown mild peribronchial thickening and he has hemoptysis. Bronchoscopy normal , the lavage showed abundent epithelial cells squamous & respiritary type quite degenerate conting not poss mostly inflammatery cells - macrophages moderate no of fat laden macrophages seen. Is that all normal?
They think his hemoptysis is from his adeniods - not convinced as another surgeon previously thought was from ganuloma in oesphagus.
It does not come from his stomach as he has had nissens fundoplication which is effective and no red blood is drawn from gastrostomy when he is coughing it up. He coughs up large amounts (bowlfuls) sparodically.
Is this high c02 normal with sleep apnea? This and his high pressure requirments, peribronchial thickening & hemoptysis don't seem to correlate with an apnea index of 11.


by National Jewish, Sep 24, 2004 12:00AM
This is too complicated for a short, speculative answer from a doctor who has never seen your son.  The best advice is that he be examined by a pediatric pulmonologist.  If he already has, you should seek a second opinion.

An ENT specialist should be able to see if blood is coming from his adenoids (adenoids).  Other tests that may be done to find the source of the hemoptysis are a high-resolution CT scan and lung vascular studies.

His adenoids (adenoids) may be contributing to the obstructive sleep apnea (OSA).  Also his tonsils, if he still has them, may be contributing.  High levels of carbon dioxide (CO2) in the arterial blood may occur with central sleep apnea.  When there is a problem with upper airway obstruction or restrictive lung disease causing stiff lungs, then high pressure could be required on the continuous positive airway pressure (CPAP) machine.
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