I had limited exposure at my workplace to a person with active, untreated TB. She eventually died from it. There has been no contact with this person since September, 2003. I had the PPD test in October, 2003 and tested negative. I was contacted by the local health dept and re-tested recently. The PPD test was positive, however, I have no symptons. I have a chest xray scheduled. The health dept has advised me that I need to take the medication, regardless of the chest xray results. I have heard conflicting information about whether the risks of the medication outweigh the benefits, if the chest xray is negative. I am 39 years old and healthy. I did have about 1/2 of my left kidney removed in 1986 due to a blockage in the urethra that caused atrophy in the kidney.
Please advise on the risks/benefits of the medication in the event of a negative chest xray.
The history of a negative PPD shortly after exposure (10/03), and then a positive PPD later is consistent with having been infected during contact with the TB patient. It may take up to 16 weeks for the PPD to become reactive after exposure/infection. If the chest xray is normal it would be appropriate to take preventive therapy or "treatment of latent TB infection" (TLTI). If you do not have underlying liver problems, there are no contraindications to TLTI. Your options include 6-9 months of isoniazid (INH) or 4 months of rifampin. All available data indicate that the potential benefits of TLTI clearly outweigh the risks.
Here's a link with details on treatment of latent TB:
Targeted Tuberculin Testing and Treatment of Latent Tuberculosis Infection
ATS/CDC Statement Committee on Latent Tuberculosis Infection Membership List, June 2000
"This statement provides new recommendations for targeted tuberculin testing and treatment regimens for persons with latent tuberculosis infection (LTBI) and updates previously published guidelines (1,2). This statement is issued in recognition of the importance of these activities as an essential component of the TB Elimination Strategy promoted by the U.S. Public Health Service Advisory Council on the Elimination of Tuberculosis, and reports the deliberations of expert consultants convened by the American Thoracic Society (ATS) and Centers for Disease Control and Prevention (CDC). "
Copyright 1994-2016 MedHelp International. All rights reserved.
MedHelp is a division of Aptus Health.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.