I have been taking Prednisone for over 16 years (7.5mg) per day and have now become dependent on it. I have asthma and crohn's disease. Is there a substitute for prednisone with less side effects for someone like me whose adrenal gland isn't producing?
I suspect that you and your doctors are aware of the other conventional therapy for Crohn's disease, including aminosalicylates, such as Sulfasalazine® (salicylazosulfapyridine), thiopurine anti-metabolites, such as azathioprine, and, of course, steroids. Entocort® (budesonide) is now considered by many as first-line steroid therapy and some people dependent on conventional therapy, such as yourself, may be switched to budesonide with benefit and decreased steroid side effects.
For your asthma, inhaled corticosteroid (ICS) therapy is preferable to oral (systemic) therapy but in some instances, may not be as efficacious.
You should discuss these considerations with your doctors.
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