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Respiratory Disorders  (Expert Forum)
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Xolair Injections
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This forum is for questions and support regarding lung and respiratory issues such as: Allergies, Asthma, Bronchitis, Colds - Flu, Chronic Cough, COPD, Cystic Fibrosis, Emphysema, Fibrosis, Lung Abscess, Nasal Polyps, Pleurisy, Pneumonia, Sarcoidosis, Sinusitis, Tuberculosis.

Xolair Injections

by WilliamB, Aug 31, 2004 12:00AM
Greetings,

A few years ago I was diagnosed with Samters Traid, an allergice reaction to aspirin, nasal polyps and asthma. After researching this further I am told that my asthma is allergy induced and that I might benefit from Xolair Injections. I am curious to her any pros and cons from participants of this forum.

Bill

by National Jewish, Sep 13, 2004 12:00AM
The immune system normally protects your body by fighting harmful things such as infections.  Allergies can start at any age.  In people who are allergic, the immune system acts in a different way.  With an allergy, the immune system reacts to something that is normally harmless.  A normally harmless substance that causes an allergic reaction is called an allergen.  With the first exposure to an allergen, there are no symptoms, but the body remembers it as harmful.  With later exposures, the immune system produces a substance called immunoglobulin E (IgE).  IgE is an antibody that tells special cells to release chemicals.  One of these chemicals is histamine.  These chemicals cause uncomfortable and sometimes dangerous allergy symptoms.  When a person has allergy-induced asthma, this will make their asthma worse.

XolairŽ (omalizamab) is an anti-IgE medicine.  By keeping IgE from working, XolairŽ (omalizamab) injections decrease the number of asthma attacks.  XolairŽ (omalizamab) is given every 2 to 4 weeks as a subcutaneous shot.  That means that it is injected just under the skin.  The dose depends on your IgE level and your body weight.  Your IgE level is measured using a simple blood test.  XolairŽ (omalizamab) injections are recommended for people with asthma symptoms that continue even though they are using an inhaled steroid on a regular daily basis and have an IgE level between 30 IU/mL and 700 IU/mL.  The XolairŽ (omalizamab) injections are usually stopped if your allergy-induced asthma has not been helped after 4 to 6 months.

The most common side effects with XolairŽ (omalizamab) injections are:  
ˇ Injection-site reaction;
ˇ Viral infections;
ˇ Upper respiratory infection;
ˇ Sinusitis;
ˇ Headache; and
ˇ Sore throat.
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