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Respiratory Disorders  (Expert Forum)
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another phenylepherine question, rebound effects
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another phenylepherine question, rebound effects

by Citizen T, Mar 25, 2006 12:00AM
Sorry to post the second time, but I used phenylepherine for 4 days at the maximum daily dosage, and now my nose feels very swolen shut even more than before(the famous "rebound effect" I assume).   I thought rebound would only happen if used more than 5 days.    I guess my question is, will my nose ever go back to "normal" without surgery or some other treatment?   Thank you.

by National Jewish, Mar 28, 2006 12:00AM
When you stop the drug your nasal membranes will go back to the way they were prior to the use of phenylepherine.  This will be back to baseline; not necessarily back to normal.  Whether your nasal condition will require surgery will depend on what is causing it and the response, for example, to nasal steroid therapy.  

Surgery is necessary for correction of a deviated nasal septum.  Nasal polyps, on the other hand, frequently respond to steroid therapy.  In the past surgery was thought to be necessary.  You may want to try doing a nasal wash prior to your nasal steroid spray. Please click on this link to read more about this nasal wash treatment.

Member Comments (2)

by myproblem, Mar 28, 2006 12:00AM
For some people, rebound happens after only 1-2 doses. I know it's miserable, but it should be better in a few days. Try Breathe Right Strips. In the future, try using less than the maximum dose, in other words use it at longer intervals, and the rebound won't be as bad. You can also try saline spray (Ayr)to clear your sinuses. Because this is not medicine, you can use it as much as you want. Do you have a sinus CT scheduled?
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