I have a PFT consistent with emphysema (FEV1 52% of predicted; FEF25-75 24% of predicted; elevated TLC, FRC, RV; DLCO 68% of predicted; poor response to bronchodilator challenge). I am a nonsmoker, 44 years old. My
alphaAlpha 1-proteinase inhibitor
Alpha e
Alpha fetoprotein
Alpha lipoic
Alpha lipoic acid
Alpha tocopherol
Alpha-lipoic acid
Alpha-lipoic-acid-300-1 antitrypsin
serumFerritin
Serum calcium
Serum globulin electrophoresis
Serum iron
Serum ketones
Serum phosphorus
Serum progesterone
Serum serotonin level
Sodium - blood level is
normalNormal saline flush. My high resolution chest CT is
normalNormal saline flush. I have had
recurrentRecurrent cystitis respiratory infections in the last 8 months. I have a chronic productive cough, shortness of
breathBreath alcohol test
Breath holding spell
Breath odor on minimal exertion, significant fatigue. Wheezing is very rare and never lasts more than a minute or so. I have not responded to Advair or to treatment for post-nasal drip or GERD, which my doctor says are the three most common causes of chronic cough in nonsmokers.
My question: with a PFT consistent with emphysema, a normal A1A level, a normal HRCT, and my symptoms, what are the other possibilities? Is it possible that the PFT is way off, especially with regard to DLCO? Is it possible that emphysema would not show up on a high resolution CT? What other obstructive lung diseases would present with my symptoms, show an emphysema pattern on a PFT, and not show up on HRCT?
Thank you.
US News has an annual list of Best Hospitals sorted under various catagories at: www.usnews.com/usnews/nycu/health/hosptl/tophosp.htm When one gets to that site click on "respiratory disorders"
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Hope this helps you--having poor lung function is scary & dangerous.
Aloha,
Starion