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succinylcholine apnea
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Avatar universal
succinylcholine apnea
could  give me  please  some  information  for the  succinylcholine-induced apnea ??information  please such as  how to identifyu the problem,the enzyme  which is  involved ,the inheritance pattern,the diagnosis,treatment  ...prevention.i have an essay on it.iam a final  year  biochem student  and  i cant find  anything  on it.is  it  possible to halp me  for  this??
thanks
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251132 tn?1198082422
Succinylcholine apnea is identified by a blood test.  There is a genetic defect that causes a lack of the enzyme that breaks down succinylcholine, a type of anesthesia.  When succinylcholine is given to a person with this defect, it continues to suppress breathing long after the general anesthesia has worn off.  For treatment the person is put on a ventilator and given fresh frozen plasma.  Family members should be tested and have genetic counseling.  Anyone who lacks this enzyme is at lifelong risk with succinylcholine.  They should wear some type of identifying tag, such as a bracelet or necklace, with this information.

You will need to check with a medical library for current references, but here are some citations to get you started on your essay:

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Avatar universal
http://www.anesth.org/contents/38/38_229-232.pdf

http://www.lhsc.on.ca/lab/updates/v3n3.htm

http://www.med.umich.edu/em/em/eddpp-backup/SedNeuroBlockingAgents.html

http://www.genomica.net/RIVISTE/NEJM/NEJM_weinsh.htm

http://www.emedicine.com/med/topic1935.htm
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