Thanks for the quick response. Amazing actually...
I wanted to use this forum as a reality check on my treatment. Also, even though my urologist is highly regarded by my doctor and seems to be highly competent, he is not the best communicator.
I became anxious after reading about the CDC recommendation in 2007 that a third generation cephalosporin is the only recommend treatment for gonorrhea in California and that I had not been treated with that class of antibiotic. Sometimes the worst part about these medical issues are not physical pain, but the emotional stress and anxiety.
It sounds like the proper steps are being taken. Also it is good know that I don't have to be on the run from romance in fear of spreading some horrible disease.
For $15 you guys provide an amazing service! Keep it up.
Reacting first to the title you chose for your question: If 5 visits to qualifed health care professionals have not come up with clear solutions to your medical problem -- whatever it turns out to be when I read the question -- it is very unlikely that a distant online forum, no matter how expert, can solve the problem.
Now I have read the question. Unfortunately, my gut reaction is confirmed.
"I woke up in the middle of the night with pain in my right testicle": An STD is a possible cause of such a symptoms, but not the most likely explanation.
2nd visit: "Doxycycline for 10 days + Mobic assuming Chlamydia": Was a test for chlamydia not done? What were your risk factors for STD? New sex partner recently? Multiple partners?
3rd visit: "thickening in the tail of the right epididymis indicating the onset of epididymitis": Epididymitis due to chlamydia or gonorrhea (the only STD causes of epididymitis) was pretty much impossible at this point, since you had already received doxycycline -- which would have cured chlamydia for sure and usually gonorrhea as well.
4th visit: Continuing symptoms despite azithromycin (Z-pak) was further evidence that an STD was not the problem.
5th visit: Continuing pain despite yet another course of azithromycin: Still stronger evidence against STD.
Subsequent improvement (but then not so much) on ciprofloxacin: There is no STD that responds to cipro but not azithro and doxy. Theoretically gonorrhea could do that, but there are many other reasons to be confident gonorrhea was not the problem. My guess is that no infection of any kind is the problem here. However, your urologist may be correct, that you had a non-STD infection with an organism of the type that commonly causes urinary tract infections, like E. coli and others.
My advice is to continue to work with the urologist about this. It is clear that no STD explains this problem.
Good luck. I wish you well --- HHH, MD