Based on your symptoms, I would be skeptical about the diagnosis of reactive arthritis. But if two rheumatologists concur in it, I will go along.
It is likely that any inflammation of certain mucous membranes, especially of the genital or gastrointestinal tract, can trigger ReA; i.e. it doesn't necessarily have to be an infection. Accordingly, I suspect your antibiotic related diarrhea is responsible. But that's little more than an educated guess.
That will end this thread. I won't have any other comments. Good luck.
Hi Doctor. I thought I'd provide an update for the sake of completeness and the education of future visitors. I used a recent trip abroad as an opportunity to get some proper testing done, including a NAAT on urine for chlam/gc (both negative) and an EPS culture (also negative). Was told that prostate was inflamed but not infected. The only prostate-related symptoms I have are frequent urination/weak stream and a noticeable change in the volume and consistency of the semen (i.e. very little pelvic pain if any). However, the aches and pains in my joints have not gone away. Several times a day I have pain in my fingers, toes, soles, elbows, wrists, forearms and around the knees and occasionally lower back. Sometimes the pain is in the joints or bones and other times it feels more like the tendons or muscles. It migrates from one place to another lasting only a few minutes each time. This started around 7 or 8 weeks ago. For the past three weeks, I've also had longer, more concentrated pain in my right ankle and occasionally my left and in the achilles, which only subsides with NSAIDs, otherwise it impairs my walking and driving (the tendon on the front of the foot especially). Two rheumatologists have diagnosed me with reactive arthritis and put me on NSAIDs for the foreseeable future. So, there must have been some infection in the past few months. The question is what that infection may have been. I do understand that the timing of the symptoms (10-12 weeks from exposure) make an STD an unlikely cause. The only other possibility is the endoscopy followed by 14 days of amoxicillin/clarthromycin which may have caused some kind of GI infection that precipitated all of my symptoms (including the urinary/prostate symptoms). I know I've tested your patience on this thread and completely understand if you decline to answer, but given your expertise in ReA I would greatly appreciate your view on the relative likelihood of these two possibilities. Thanks.
I don't know anxiety explains your symptoms. With the additional information that your doctor has diagnosed infectious prostatitis, perhaps that's the only issue. All I can say for sure is that it's neither gonorrhea nor any other STD is the cause.
It is certainly a "realistic possibility" that you could acquire an E. coli prostate infection. It's rare at your age, but rare things sometimes happen. Still the lack of response to antibiotics suggests E. coli might not be the main cause of your symptoms. The reasons prostatitis is more common in older men are pretty complex, and beyond the scope of this forum, which is limited to STDs. All these are issues for you to discuss with your doctor.
That will end this thread. You can dismiss STDs entirely, and you should disregard any past sexual exposures. You have no infection from such an event.
Thanks, Dr. I respect your opinion even though I find it odd that anxiety-generated symptoms would take 10 weeks to show up and do so so abruptly. I know you don't want a long discussion or a re-tread over ground we've already covered, but if you can answer the following question that would be greatly appreciated:
My doctor's diagnosis is not CPPS (though he did mention it) but bacterial prostate infection due to e choli, strep or some other bacteria. Is it a realistic possibility for a 31 year old to get that kind of infection? How does it come about and why does its occurrence vary by age?
I meant to also say that failure of your symptoms to improve with antibiotics is evidence NOT of an infection that is resistant, but rather evidence that no infection of any kind is going on. Most prostate problems are non-infectious (antibiotics are often tried but usually don't work). This is additional evidence that the real problem is genitally focused anxiety or CPPS (which itself often is just the result of anxiety, as you will see in reading about it).
And by the way, CPPS or genitally focused anxiety are often triggered by sexual exposures that cause regret, guilt, or shame. Your username suggests this is likely in your case.
Let's not get into a prolonged discussion as in your previous thread. There is no information you can provide that would be likely to change my opinion or advice, so I won't have any further comments. If your symptoms or other concerns continue, keep working with your primary care doctor about it.
I'm sorry to learn your symptoms and anxieties are continuing following our previous discussion on this forum.
I agree with your doctor. Your symptoms are not possibly due to gonorrhea or any other STD. Gonorrhea doesn't cause the sorts of symptoms you describe, but they are typical for a prostate problem or the related condition called the chronic pelvic pain syndrome. (Look it up on Google and start your reading with the excellent Wikipedia article.) And if you had had gonorrhea, the treatments you have had would have cleared it up.
You need to stop any further STD testing. If you have a regular partner, you should continue or resume unprotected sex. You have nothing that will ever cause serious harm either to you or to her; in fact, regular sexual release sometimes is helpful in symptoms like yours, whether due to a prostate problem or CPPS.
Best wishes-- HHH, MD