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Low Positive HSV II
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The STD Forum is intended only for questions and support pertaining to sexually transmitted diseases other than HIV/AIDS, including chlamydia, gonorrhea, syphilis, human papillomavirus, genital warts, trichomonas, other vaginal infections, nongonoccal urethritis (NGU), cervicitis, molluscum contagiosum, chancroid, and pelvic inflammatory disease (PID). All questions will be answered by H. Hunter Handsfield, M.D. or Edward W Hook, MD.

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Low Positive HSV II

I got results back from an HSV 1 & 2 (igg)test last week.  Results came back negative for HSV 1, but positive for HSV 2 (score of 2.4).  I retested a couple days ago at LabCorps through STDtesting.com (herpeselect HSV 1 &2 igg test).  I just received the scores---HSV 1--negative; and HSV 2 (score of 1.47).  Note:  I do not have any symptoms and use condoms regularly.  I asked the doctor via the testing service about false positives--especially if the scores were below 3.5.  I told him I've researched the matter and heard that it was worth retesting.  He was immediately dismissive of "whatever I read" on the internet.  He said my score might fluxuate--but if I've tested positive...I would always be positive---even if I retested.  He was also saying that even though i don't have symptoms--i could probably have them later in life.  He said that people who don't have symptoms have really strong immune systems, meditate, or have acquired strong immune systems from family.  

Anyways--would appreciate your thoughts on how to proceed (or if I should give up).  Also--is it unusual for my score to go from 2.4 to 1.47 within a week?  Is there any signficance to that?

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Welcome to the Forum.  I agree with what you have already hear from the HSV Community site- the values that you have on these two tests are in the range where false positive test results are relatively common with over 50% of such values being found to be falsely positve.  My advice would be to seek a "tie breaker" and to seek testing with a Western blot performed at the University of Washington. Alternatively, testing with a Biokit or Sureview test may be helpful. If you have a Western blot assay which is negative for HSV-2 or "Indeterminate" then your result is falsely positive. Similarly, if the Biokit/Sureview assay is negative, this too suggests that your HerpeSelect tests are falsely positive.  

The fact that your test went result went from 2.4 to 1.47 within  a week does not carry any particular significance.  

I hope my comments are helpful. EWH
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