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STDs  (Expert Forum)
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Tolerance to Aldara?!
Answered by
University of Washington Seattle - WA
Welcome to the STD Forum, which is intended only for questions and support pertaining to sexually transmitted diseases other than HIV/AIDS, including chlamydia, gonorrhea, syphilis, human papillomavirus, genital warts, trichomonas, other vaginal infections, nongonoccal urethritis (NGU), cervicitis, molluscum contagiosum, chancroid, and pelvic inflammatory disease (PID). All questions will be answered by H. Hunter Handsfield, M.D. or Edward W Hook, MD.

Tolerance to Aldara?!

by DancingBrave, May 04, 2005 12:00AM
I was using aldara and it cleared be about 90%+ in about a month. Then it stopped working entirely...Have you heard of  anything like this or know why it might happen. Thanks in advance for the help.

by H. Hunter Handsfield, M.D., May 04, 2005 12:00AM
That happens all the time.  Whatever treatment is used - imiquimod (Aldara), podofilox (Condylox), freezing, trichloroacetic acid, and others - it is common for warts to respond initially and then become resistant.  Overall, Aldara is effective in eradicating warts about 60-70% of the time.  Check with the provider who prescribed your treatment; the first thing is to be certain you really have persistent wart tissue and not just a heaped up scar.  But assuming it's a wart, you'll need to try one of the other treatments.

Good luck--  HHH, MD
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