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Avatar universal

test of herpes simplex 1 igg and test of simplex 2 igg

hi, i had recently test my herpes  2 times  one  day after another and i had this 2 different result:

first time:
herpex simplex 1  Igg positive  value 5.32
herpex simplex 2 Igg negative < 0.91

the second day i had this result
herpex simplex 1 igg positive 4.82
Herpex simplex 2 Igg positive  1.534


now my question is do i have to retested or based on this result i can say that i have both virus?
or i have only herpex 1 which i actually Know to have it because i had all my life frequent outbreaks on my lips ?
i don't have any sign on my genitals at the moment .
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239123 tn?1267647614
MEDICAL PROFESSIONAL
No.  Your wife's positive IgM result probably is meaningless, and I strongly recommend you not have an IgM test.  Below is a thread that explains why; even though it's 5 years old, the information remains accurate.

http://www.medhelp.org/posts/STDs/Confusiion-over-other-IgM-Herpes-posts/show/248394
Helpful - 0
Avatar universal
Hi Thanks For The Answer i hope With All My soul that What i say Is true cause My wife Was recently found positive With My same result as The second day. But She also had an IGM that Was Hi in value And positive?
I Was suggested to test IGM too.. Does this make sense to u?
Helpful - 0
239123 tn?1267647614
MEDICAL PROFESSIONAL
Welcome to the forum.  I'll try to help.  To start, however, I'm quite curious why you had 2 HSV blood tests a day apart.  You should have stopped with the first -- then there wouldn't be any confusion about your negative results!

As you have learned, the HSV blood tests can give quite variable results.  The bottom line is that you are definitely infected with HSV-1, and probably not HSV-2.  Even though the official cut-off value of a positive HSV-2 antibody test is 1.1, in the large majority of truly infected people the test produces values of 3.5 or higher (as for your HSV-1 results).  Most results around 1.5 are falsely positive.

So basically you have had two negative HSV-2 results -- one definitely and officially negative and the other, only a day apart, weakly/borderline positive and probably false.  You can safely conclude you are not infected with HSV-2.  No further testing is necessary.

I hope this helps.  Best wishes--  HHH, MD
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