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Tired from medications?
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Tired from medications?

My 61 yr old husband is so tired that he takes 2 naps daily and even though he is depressed, he is positive his fatigue is not due to this..  He uses a CPAP(successfully except he jerks it off w/o remembering several times a night.  He also still jerks his arms and sometimes has a tremor while sleeping and usually does not remember this.  He has emphesema w/no oxygen.  Meds include lamotrigine, luvox, pramipexole DI-HCL, amantadine, Advair, Simvastavin, bisoprolol and , lisinopril .  2 MRIs showed nothing. Thank you.
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Hi, welcome to the forum, there are many causes of tiredness. Main cause for tiredness is weakness of one or more muscles in extremities. Some causes for loss of strength in arms and legs are disorders of neuromuscular system, Electrolytic imbalance, hypokalemia, injuries, metabolic diseases, toxins, trauma, severe sprains etc we cannot rule out the exact cause without medical findings.

He needs to undergo certain blood tests like blood electrolytes (sodium, potassium, chlorides etc.), blood sugar and ESR. Yes, medications can also cause such tiredness. Lamotrigine, pramipexole and amantadine are known to cause tiredness or weakness. Drugs like bisoprolol and lisinopril can raise the potassium levels and precipitate the weakness.

A detailed physical examination should be done which can point out the cause and specific investigations can be done for early diagnosis. Treatment should be directed toward the underlying etiology. Electrolyte abnormalities, metabolic abnormalities, or nutritional deficiencies should be corrected. Take care and regards.
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