Immunological Causes of M/C?

[Sherri90049]

Does anyone have experience with m/c due to immunological causes? And if so, were you successfully treated for it and then able to have a successful pregnancy? I have lupus w/elevated anti-nuclear antibodies (ANA) and slightly elevated antiphospholipid antibodies (APA) and I also have autoimmune thyroiditis w/elevated thyroid peroxidase antibodies (TPO). My symptoms until now had not warranted much in the way of treatment, but with my recurrent early m/c's (7!), I feel that it's time to take action to treat this stuff. From what I've read, it looks like I could be really helped by: prednisone, aspirin/heparin, thyroid medication (synthroid), selenium supplementation and possibly intravenous gamma globulin. I have an appt on 4/13 w/my RE and my endocrinologist, so I'm hopeful that we can make a plan. I want to try again as soon as possible, but not until I can be sure that some of these potential immune causes can be treated. SSBD!

[Sherri90049]

Thanks for responding! Will look around for an autoimmune board! I hope my RE "gets it" when I see her tomorrow. I strongly believe that the cause(s) of my m/c's are immune in nature. I've been researching all night on the internet and I actually read that even having a high FSH (mine was 57 last month!) can be caused by immune problems! (which would make sense considering I am not at all in menopause, ovulate every month and have conceived so many times) :-)

[Pum]

Sorry I can't help on this one. I have some sort of minor autoimmune arthritis (only one major joint flare over 10 years ago and nothing major since thank goodness). 7 m/c definitely warrants you taking it further and I hope they can help you. An autoimmune support board will no doubt have heaps of women that have had successful pregnancies.

Take care.