I was having high blood pressure problems starting about four years ago. My doctor put me on a dieuretic (water pill) along with my blood pressure medicine. I also have a GERD and take a stomach pill and eat a lot of tums. I have been running a high serum calcium level for several years now. I have had the following reading on serum calcium from 2007 to 2009. 10.5, 12.9, 10.9, 10.7, 11.0, 11.4, 10.6. I have had one PTH level done about a week ago and it was 46. I just had an ionized calcium level done and it was 5.7. I had a parathyroid ultrasound done last week and it did not show any parathyroid problems. I had a chest xray done and a test for sarcoidosis, it was negative. I have blood work out now to check for multiple myeloma. I discontinued the dieuretic last week and went on a dairy free diet per my doctor's orders. I asked him if this could be a parathyroid problem and he said no. He thinks it is being caused by the dieuretic. He is referring me to an endocrinologist. What do my doctor is on the right track?
You likely have primary hyperparathyroidism. The calcium can be increased slightly by HCTZ (the diuretic) but with this history and labs you likely have primary hyperparathyroidism and the ultrasound was not able to find the adenoma (about 75% are identifiable on ultrasound).
The PTH is inappropriately normal for this degree of elevated calcium.
Thank you so much for your response to High Calcium Levels posted by tam200 on Feb. 25, 2009. I have some new information since my posting. My primary doctor sent me to a Oncologist/Hemotologist. He said there was a monoclonal protein in my blood. He mentioned the IgG protein. The Hemotologist said he is working me up for multiple myeloma. He took more blood work and had a bone scan done. I ask him about the PTH level being 46 with the high calcium levels. He just said that the parathyroid was not the cause of the high calcium. He said the best case scenerio would be MGUS. I guess my question is twofold. First, even though I have this monoclonal protein would it still be possible for the parathyroid to be causing the high calcium levels? Second, If it was the monoclonal protein or myeloma causing the high calcium levels wouldn't the PTH level be very low?
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.