Thyroid Cancer / Nodules & Hyperthyroidism Expert Forum
How normal are thyroid antibodies?
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Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

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How normal are thyroid antibodies?

Dear Dr. Lupo:

Does having any detectable thyroid antibodies are of any significance?

I just had a full thyroid panel and wonder if the antibodies results are of any significance:

TSH - 1.54 uIU/mL (0.35 - 4.94)
T4 Total - 8.55 ug/dL (4.87 - 11.72)
T Uptake - 43.3 % (32 - 51)
Free Tiroxine Index - 9.26 ug/dL (5.93 - 13.13)
T3 Total - 1.03 ng/ml (0.58 - 1.59)
T3 Free - 2.90 pg/mL (1.7 - 3.7)
T4 Free - 1.37 ng/dL (0.70 - 1.48)
Thyroglobulin Autoantibodies - 26.6 U/mL (Reference range 0-34)
Thyroid Peroxidase Autoantibodies - 5.5 U/mL (Reference range 0-12).

I was told that sometimes the lab equipment that measures the antibodies will never give you values of zero, but I really don't know.

Thanks and your help is greatly appreciated,
Roberto
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Thyroid antibodies within the reference range are considered normal.  While it seems that normal should be "zero", low levels of antibodies (even against parts of our own body!) are seldom clinically significant.  I would interpret the thyroid panel and antibodies as normal and check a TSH yearly to screen for thyroid disease -- which based on the above data you are at low risk to develop.
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mine measured 1500 once and in the 300's another time...Just for a reference.  I was diagnosed with Hashimoto's.
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