Not sure what's going on?

[snarky348]

Hi,  I'm a 33 male and I've gained alot of weight in the past few years... went from 220 up to 305.  All along my TSH was normal,  even 6 months ago it was about 3.3 and just now I've been tested at a little over 6.5.    

The thing is, and I don't know if any of this would be related (but I've read that hypothroid is usually caused by an autoimmune attack),  but in the last few years I've had various odd inflammations in my body.  First it was my stomach with non infectious duodentitis as proctitis with bowel changes (confirmed with endoscopy).  Then those went away, and for a long time I had fluctuating atypical chest pain which never was explained.  

Now, just recently there is something wrong with my bladder area that feels like inflammation that fluctuates,  but when I went to see my doctor about it he also tested my TSH and that's when I discovered it's 6.5.

Question is,  is something going on with the larger picture that I've had all these inflammations that each other them lasted for months and then subsided and it's as it whatever it was just moved on to a new part of my body?   I also had my ESR tested and it was normal.

My doc wants to put me on Synthroid for my 6.5 tsh without doing any additional antibody tests or anythign that I'm aware of,  does this seem appropriate to you?  

I always have my doubts about the decisions of any given one person so I'd love to hear your opinion about all this.  Thanks again.

[Roro2011]

Hi,

I have a 2.5cm nodule, suspicious for neoplasms. This area of my neck has occasional discomfort, or throbbing, and I have had a biopsy, multiple blood works, urinalysis, ultrasounds, etc. Every blood test and urinalysis shows my hormone levels (TSH and T3, T4) and calcitonin levels within normal range, and I have not experienced any changes in my weight. My only change I have experienced is exhaustion (vitamin B is added to diet now), and throbbing occasionally (before and after the biopsy). My doctors all say that the nodule is not associated with pain. I have seen 2 endocrinologists, a surgeon of endocrine tumors, and my pcp.

Any suggestions on what is going on or causing this discomfort? I am awaiting a follow-up appointment, but it will determine if the nodule needs to be removed.

Thank you in advance!

[snarky348]

By antibodies do you mean TPO?

[Mark Lupo, M.D.]

Usually would repeat TSH after 6 weeks and test antibodies to confirm abnormality and test for Hashimoto's.