Thyroid Cancer / Nodules & Hyperthyroidism Expert Forum
TSI antibody question
About This Forum:

Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Blank Blank

TSI antibody question

Do you feel that the TSI antibody test is the definitive test to determine graves disease, and if so, is it the test that determines when remission has occured?  So if the antibodies go below or into the normal range then graves is gone?

Thank you,
Lorilynn
Related Discussions
97953_tn?1193367871
TSI is not the definitive test but is very helpful.  TSI and TBII (aka TSH-receptor antibodies) tend to normalize with remission and this normalization helps predict remission -- they will not go below the normal range though.

TSH-R-Abs are useful beyond the diagnosis in my opinion particularly when predicting remission and noting severity of graves eye disease.
5 Comments
Blank
259041_tn?1206486447
the author Elaine Moore, who wrote books on Graves says that normal people have no tsi or 2 percent, I think. Mine was 109 at diagnosis, even though the normal goes up to 125, that's bull! Some just don't feel symptoms till they reach that. I had an uptake scan too, which was normal but on the high side. I have heard the TRab test or the TBII is supposed to show remission. My doc argues this, he says it's just for diagnosing Graves. What was your TSI? What are your labs? Are you on meds?
Blank
Avatar_n_tn
My TSI at DX was 232.  my starting labs were, TSH o.o1 (o.3-5.7) FreeT3 5.45 (1.5-4.1) FreeT4 2.03 (0.58-1.64)  I started on 20mg of MMI a day for a month until I went hypo, I am now for the past almost 8 mos on 5mg of MMI a day and 50mcgs of synthroid.  my last TSI of Jan 08 was 155.
Blank
Avatar_n_tn
Hello here,
I dx with Graves a year ago, after PTU for 6 months went Hypo. You are the same case as me. My question is: Why are you still taking antythyroid medication together with synthroid? I want to just drop my slowly and maybe go on remission.
Elena
Blank
259041_tn?1206486447
this is called the block and replace method. you are given a small dose of Tap or ptu and to keep you from going hypo a little of synthroid too. In Japan this is used often, but not really in this country. It supposedly has a good success rate too. I don't know what the reason is that it's not used here much.
Blank
Continue discussion Blank
MedHelp Health Answers
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
RSS Expert Activity
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank