It should not effect the TSH - and would have small impact on T4 -- so ok to take med morning of labs.
If you are having thyroid lab's drawn I would wait until after. They say it doesn't matter but I have experienced an extremely low TSH the day I took my replacement and had thyroid lab's drawn.
I do.
GL
Hyper/Graves'/RAI
L-T4 (synthroid, levoxyl, etc) can be taken the same day. After all, the medication is accumulative.
"TSH testing is not influenced by the time of day the L-T4 dose is ingested".
However, Central hypothyroidism, the daily dose of L-T4 should be withheld on the day of testing.
Complete Summary GUIDELINE TITLE Laboratory support for the diagnosis and monitoring of thyroid. guideline.gov (government)
National Academy of Clinical Biochemistry (NACB). NACB: laboratory support for the diagnosis and monitoring of thyroid disease. Washington (DC): National Academy of Clinical Biochemistry (NACB); 2002. 125 p. [495 references]
You can take your thyroid meds the same day and before test.
GL
Hyper/Graves'/RAI