Thanks for answering my questions and everyone else for that matter. Its a great service to a lot of worried people. I have been on methimazole for about 6 days now and I know everyone said its takes a couple of weeks to kick in. My worry is that Im taking 50mg atenolol in the am, 25 in the afternoon, and 50 at night plus the20mg a day of methimazole. Yesterday I had another spike at 198/96 and 88P. This scared the heck out of me. Should that happen with the meds Im taking. This was when I first woke up in the morning and walked into the other end of the house and took my bp then. It went down after about 5 minutes. Ive had this happen over the past 5 weeks or so about 4 or 5 times now. Also the Dr. gave me diazepam that I could take but only have taken 1/2 of a 5mg tablet no more than once a day. Should I take it more often? I dont like getting hooked. Do people have panic attacks just waking up and have that kind of spike? Will this go down when the methimazole starts working? Your so helpful and thanks again.