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Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

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by Seretse, Nov 01, 2008 01:34PM
I had a hyperthyroid condition and had radiation to reduce the hyper.  I was placed on Synthroid but now have been given Levothyroxin (levothyroxine).  I noticed on your discussion board that the latter is a generic.  Now, what I would like to know is which is the best medicine I should be taking and how should I approach my Endocrinologist for a change in prescription.

I want to thank you very much for having this message board to solve problems.  This is great and your are to be commended for taking time to answer questions.

by Mark Lupo, M.D., Nov 02, 2008 12:23PM
Levothyroxine is T4 (a bio-identical copy of the T4 your thyroid made).  Synthroid is one of the brands of levothyroxine, Levoxyl and Unithroid are other brands.  There are also several (around 8) generic producers. The key is consistency -- if your pharmacist can always get generic T4 from the same source, that usually works as well as a brand and can save money.  If not, then there may be fluctuations in the response to the T4.  In general it is recommended to "protect the brand" to ensure consistency.
Member Comments (2)

by klassylady25, Nov 02, 2008 07:15AM
To: Seretse
I'm not a doc but I can tell you that if generic is taken that of times you will experience differences in the body.  Though generic has the same meds, the filler that is used to bind causes the medication not to be absorbed properly in the body and thus causes flux in the way it's suppose to work.

Ask your pharacist.  I've been on Levoxyl 125mcg for over 10 years.  The two times my physician tried to switch me to Levothyroxin (levothyroxine), was bad news for me however, I have 1/2 a thyroid and I do not know your condition.  Something to think about though.

Candice
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