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Can Prevacid interfere with your thyroid hormone replacement?
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Can Prevacid interfere with your thyroid hormone replacement?

by j.drake, Dec 16, 2005 12:00AM
Dr. Mark,

I am currently taking Synthroid (150mg) and Cytomel (5-10mg) and starting taking Prevacid for chronic heartburn about a month ago (after a bout of stomach flu) I had never suffered from heartburn before in my life.  In the last few weeks I've had severe fatigue, weight gain, my skin and hair are much drier, bloating in the stomach, a hard time sleeping at night and a feeling of fullness for up to 16 hours after I eat.  I am wondering if the Prevacid is interfering with my thyroid medication?  Is this a possibility?  Or is it something else?

Thanks!
Jenni

by Mark Lupo, M.D., Dec 16, 2005 12:00AM
It's possible that the change in stomach acid has changed the absorption of thyroid meds - best way to know is to repeat the thyroid labs and see what's happening.
Member Comments (3)

by j.drake, Dec 23, 2005 12:00AM
To: Dr. Mark
Dr. Mark,

I had my levels tested and their were very low.  Is there anything else I can take for the heartburn that won't interfere with my thyroid meds?  I am currently taking Zantac and that doesn't seem to help at all.  I have also tried Tagamet, Tums and Rolaids and have had no luck with any of them.  Thanks for your help!

Jenni

by Mark Lupo, M.D., Dec 27, 2005 12:00AM
would stick with the prevacid (as it works for the heartburn) and adjust the thyroid meds as necessary following labs every 5-6 weeks until appropriately titrated.
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