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Changing TSH Levels
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Changing TSH Levels

by nalh, Dec 10, 2005 12:00AM
Hi,
Besides any sort of medication, can you please tell me what can cause changes in TSH levels?  Within the past few years, I'm mainly in the upper 3s, but last Sept I was low (.2), and I am now higher (7.85).  Is it a big change to go from 3.7 to 7.85 from Aug to Nov?  I'm testing negative for antibodies and started on synthroid a couple of weeks ago (50).  Thanks.

by Mark Lupo, M.D., Dec 11, 2005 12:00AM
High soy diets can inhibit thyroid function and increase TSH.  Also significant illness can alter TSH.  My guess is that you have antibody negative Hashimotos -- an ultrasound would show subtle changes.  The synthroid sounds appropriate.  The only non-consistent data point is the 0.2 TSH level in 9/04 -- as long as you are followed closely it should be fine.
Member Comments (6)

by nalh, Dec 11, 2005 12:00AM
To: Dr. Mark
On the high soy thing-- I had replaced dairy with soy and brought that up to my endocrinologist-- he is of the opinion that it can exacerbate a problem but not cause one if it doesn't exist, and points to all of the people in Asia who have tons of soy in their diets.  Do you agree with this or do you think soy alone can cause the change?  Thanks again.

by nalh, Dec 11, 2005 12:00AM
To: Dr. Mark
Another thing-- sorry-- should I ask for more tests of any kind?  You mentioned the possibility of TSH change caused by illness, should I look into the possibility there is something else going on? MANY thanks.

by Mark Lupo, M.D., Dec 11, 2005 12:00AM
the illness I meant would be severe (hospitalized).

The soy may aggravate a problem even if its not there -- but I tend to agree this is usually seen in patients with underlying thyroid disease.

I don't think additional testing is necessary except an ultrasound could be considered to look at anatomy of the thyroid.

by nalh, Dec 12, 2005 12:00AM
To: Dr. Mark
Sorry, one more question, then I'll try to leave you alone.  I just got a copy of my blood tests, and my testosterone was 16 (range 15-70).  My LH/FSH ratio is b/t 2-3.  I'm a 38 yo female; my periods are suppressed with Mirena.  Combined with a high TSH, does this mean anything?

Thanks again.

by nalh, Dec 12, 2005 12:00AM
To: Dr. Mark
One more piece of info-- my percent free testosterone was 1.8-- right at the high edge.  My Free testosterone was 2.8 (rnage 1-8.5).  DHEA-S 187.
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