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Enlarged thyroid lobe while on levothyroxine
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Enlarged thyroid lobe while on levothyroxine

by bluphoenixangel, Oct 29, 2007 10:47AM
I Aug. i had an U/S which showed my left thyroid lobe to be enlarged. While on my levothyroxine my TSH T3 and T4 levels were normal. Diagnosed with hypothyroidisnm in 2004. Had uptake and scan and said abnormal uptake and scan demonstrating findings consistant with Grave's Disease. Off meds for over a month before scan.  How can i go from normal levels while on Levothyroxine to having hyperthyroidism in a scan? What causes a goiter to be on only one side?

TSH 3.60
T4 0.91
T3 1.20

by Mark Lupo, M.D., Oct 29, 2007 09:22PM
One cannot diagnose hyper on a scan -- you can have elevated uptake with Hashimoto's hypothyroidism (ie elevated TSH causing increased uptake) -- this is a common confusion in reading these I-123 scans.

goiters can lack symmetry, would not worry too much about this.  If the hypo does well with levothyroxine, would continue on the dose that keeps things stable.  Ultrasound is a better way to evaluate goiter than I-123 scans.
Member Comments (3)

by bluphoenixangel, Oct 29, 2007 10:49AM
To: bluphoenixangel
Forgot to mention losing most of my voice, coughing to catch my breath if i talk too loud or try to yell. Neck discomfort.

by bluphoenixangel, Nov 05, 2007 06:00PM
To: Mark Lupo, M.D.
Had sub-total thyroidectomy on Thursday. Found it was a good thing i opted for surgery being as it was wrapping itself along the inside of my neck. During surgery i lost 200 cc's of blood, but came out if it with my voice and feeling better than i had in a while. My surgeon advised me that radioactive iodine would not have remedied my problem and that it lookes like Hashimoto's Thyroiditis. I should get the pathology report in about a week with definate findings. Thank you for your assistance.
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