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Hashimoto's disease and TTC
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Hashimoto's disease and TTC

by Ruby9Noel, Nov 19, 2008 12:27PM
I am currently 36 and have had hypothyroidism for at least 14 years and have rarely had any symptoms. I have taken my synthroid faithfully and conceived VERY easily in '05 with a VERY smooth pregnancy and healthy child. I have recently been told I have Hashimoto's disease w/ antibodies <1000 and that I should not TTC at this time due to potential birth defects and high risk pregnancy (miscarriage). My endocrinologist has me on a level of synthroid that is an attempt to flush out the antibodies. I have read several success stories that as long as my levels are being monitored as they have been for years and were during pregnancy that I can have another normal successful conception and pregnancy. I'm trying to get to the ground truth once and for all. Please advise.

by Mark Lupo, M.D., Nov 20, 2008 05:30AM
You've likely had hashimoto's w/ high antibody levels all along -- the current understanding is that proper levothyroxine treatment (ie synthroid) decreases the risk of miscarriage back to the expected rate (about 15% of pregnancies).  It may help "flush out" the antibodies but that is usually not what is followed -- more important is to keep the TSH in the 0.3-2.0 range before and during pregnancy.  This sometimes requires an increase in synthroid dose.
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