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Thyroid Cancer, Nodules & Hyperthyroidism (Expert Forum)
High antithyroidglobin
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida
Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.
High antithyroidglobin
by mw1247, Jul 24, 2008 03:45PM
Our daughter's doctor told her that her antithyroidglobin levels were 29,000. Is that possible? That is not a typo. Also, our daughter is 34 engaged to be married and would like to have children one day. Will she be able to have children? Thanks for your help.
mw1247
mw1247
Doctor's Answer
by Mark Lupo, M.D., Jul 25, 2008 05:59AM
, Jul 25, 2008 05:59AM
This is a high level, but the degree of elevation is not necessarily clinically important. Would also look at TPO antibody. If the Tg is this high and TPO negative, would certainly look at neck ultrasound b/c I would imagine there is a goiter/nodules (and there may be a need for FNA biopsy). If the TPO and Tg antibodies are both high then it is more classic autoimmune thryoid (usually Hashimoto's) and a look at thyroid function is important. Furthermore, there is a risk of infertility and miscarriage with positive antibodies -- a recent study suggested that even with normal TSH, the risk of miscarriage increases w/ positive antibodies -- but showed that even in these cases treatment w/ levothyroxine decreases this risk. So -- most in this situation will be able to have children w/ proper monitoring/management of the thyroid condition.
