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How high is my Thyoglobulin, and what does it mean
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

How high is my Thyoglobulin, and what does it mean

by Sudhah, Jun 13, 2008 01:38PM
I just got my thyroid test results as below
TSH - 7.2 mIU/L - high
Free T3 - 311 pg/dL - normal
Free T4 - 1.3 ng/dL - normal
Tpo antibody - 46 IU/mL - high
Tg antibody - 262 IU/ML - high where the normal is <20

My Tg level seems to be way too much compared to the normal, but want to check if that is correct. I am wondering what it means to have Tg so elevated. does this mean that I cannot have successful pregnancy till this is corrected (I had a miscarriage at 8 weeks before and probably pregnant now)

by Mark Lupo, M.D., Jun 13, 2008 08:49PM
This means you have autoimmune thyroid disease (hashimoto's) -- the antibodies are "positive" and the degree of rise is less important than the fact they are positive.  In terms of pregnancy, this increases miscarriage rate and infertility.  The TSH is too high, particularly if considering pregnancy or are pregnant -- would start treatment as soon as possible, in most cases would start with 100mcg of levothyroxine if you are already pregnant perhaps lower if not --- but talk to your doctor about specifics of dosing.  Treatment significantly reduces pregancy related risks and usually results in successful pregnancy.
Member Comments (2)

by Sudhah, Jun 14, 2008 03:04PM
To: Dr Mark Lupo
Thank you Doctor.
I just started on Synthroid 75mcg. And today found out that I am pregnant (5th week).
I read that hypothyroidism  in the mother could effect baby's mental abilities. I don't want this to happen to my child, knowingly. But is that true? Please suggest me. I would rather take the pain now than to cause pain to myself and the child for life.
I am not able to get an appointment with my doctor to talk about this soon.
Please advice.
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