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Thyroid Cancer, Nodules & Hyperthyroidism (Expert Forum)
Hurthle cell change
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida
Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.
Hurthle cell change
by kerile, Jul 03, 2009 01:54PM
Is there anyone who knows if Hurthle cell change frequently appears in multinodular goiterChronic thyroiditis (hashimoto’s disease)
Goiter
Graves disease
Toxic nodular goiter or only appears with Hashimoto's or cancer? My endo is three hours away and I can't get an appointment until October...... If anyone has any clue please let me know.
Thanks!
Goiter
Graves disease
Toxic nodular goiter or only appears with Hashimoto's or cancer? My endo is three hours away and I can't get an appointment until October...... If anyone has any clue please let me know.
Thanks!
Doctor's Answer
by Mark Lupo, M.D., Jul 03, 2009 06:38PM
, Jul 03, 2009 06:38PM
Hurthle changes are common in thyroid FNA samples and are associated with Hashimoto's, Graves and less commonly toxic nodules. The key is the pathologist reading the slides -- should be an expert (to avoid unnecessary surgery due to over-concern about the presence of hurthle cells). Usually lesions that are "suspicous for hurthle neoplasm" have >75% hurthle cells and no lymphocytes and little colloid -- these carry a 20% risk of cancer.
