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Hypo & TPO antibody issues
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Hypo & TPO antibody issues

by sueda1970q, Apr 25, 2008 01:00PM
Hello Dr,
I have been hypo for 10 years now. I am a otherwise healthy 38 yr old woman with 2 miscarriages that hapened last year.

Since then I have been seeing an endo, and he has recently put me from 88 (last yr)  to 100 up to  recently 112 mcg of Synthroid. I also have high TPO antibodies. (which he said may have ended the pregnancies in the first trimesters)

I just found out I am pregnant once again, and do I just assume that the miscarriage will happen again or is there hope since I am taking a higher level of Synthroid? I do have an appt with my dr next week, for blood tests.

Also, I am confused about soy consumption; should I cut it out of my diet entirely?
thank you for reading my question.

by Mark Lupo, M.D., Apr 25, 2008 02:47PM
The best we can do is keep the TSH in range -- 0.3-2.0 is ideal.  Soy should not change thyroid levels significantly with this history (hashi w/ near full replacement levels).  Monitor thyroid function tests every 4-6 weeks during pregnancy and note that synthroid dose requirements increase on average 25-40% during pregnancy.  Don't assume another miscarriage will happen -- optimal replacement reduces this risk.
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