Pain is not usually related to the thyroid or parathyroid -- if pain persists, would see an ENT doc to see what he/she thinks. 75% of incidentally found large parathyroid glands are NOT overactive - the calcium would not help this necessarily, but also would not hurt in most cases. Sounds like it should be followed -- sometimes it is tough to distinguish a parathyroid adenoma from a thyroid nodule from a lymph node on the trachea.