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Please explain distinction between follicular diagnosis and papillary.
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Please explain distinction between follicular diagnosis and papillary.

by medhelpjunkie, Apr 08, 2007 12:00AM
Can someone please expain when an FNA is done on a nodule that turns out to be follicular type cell/hurthle cell in nature, they seem to come back indeterminant or suspicious, therefore requiring to go in and remove lobe/nodule to see if it is encapsulated for it to be begnign or malignant. However, if FNA diagnosis papillary, is it automatically charaterized as malignant and surgery to remove the whole thyroid is automatically performed. I had Hurthle Cell Neoplasm, which turned out to be an adenoma. A friend of mine FNA turned out to be Papillary..and she is scheduled to have the whole thyroid removed. Just trying to better understand this wacky gland. Thanks to anyone who can shed some light on this.!!!!

by Mark Lupo, M.D., Apr 13, 2007 12:00AM
Papillary cancer (PTC)  has abnormal cellular changes whereas follicular CA and Hurthle CA have an abundance of normal cells but these cells invade the capsule or blood vessels -- this is why surgery is needed to make the diagnosis in 'indeterminant' cases.

Your friend needs a total thyroidectomy based on the FNA showing PTC.
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