Member Comments are provided by individuals and reflect their personal opinions only. Under NO circumstances should you act on any advice or opinion posted in this forum.  ALWAYS check with your personal physician before taking any action regarding your health! MedHelp International and our partners, sponsors and affiliates have no obligation to monitor any comments posted on this site, or the content and/or accuracy of such exchanges. MedHelp International does not endorse the views of any user.
 | 
Synthroid vs. Generic
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.

Synthroid vs. Generic

by Kristin6, Aug 19, 2007 01:03PM
I was diagnosed in May '05 with Hashimotos.  I began taking generic Levothyroxine and was doing really well on it.  As far as I know, I had always taken the Sandoz brand at .75mcg.  In October, when I could no longer consistently find the Sandoz brand and found that switching manufacturers really messed me up, my Dr. switched me to strictly Synthroid.  By February my TSH was back to 5.9.  I switched to .88mg and my TSH came to 2.5 but I still felt terrible.  

I've been on .100 for 3 weeks now.  I supose my TSH is still improving, but  I'm lathargic, fatigued, not sleeping, and losing my hair again.

I remember feeling tons better after just 2 weeks on the Sandoz pill.  Why does the Synthroid seem to take so long to adjust my levels?  And why do I still feel so sick when my TSH is looking better?

by Mark Lupo, M.D., Aug 21, 2007 06:08AM
TSH of 2.5 is just a little high -- target is around 1.0

Consistent source of thyroid medication is important -- all these meds have the same levothyroxine ingredient but are not necessarily the same in terms of effect on body -- so re-titration is needed when you make a change.  Now the key is to consistently get the same source each time.
Member Comments (2)

by lknnc, Aug 19, 2007 09:55PM
To: Kristin6
I believe I read somewhere that the Sandoz brand is 25% stronger than the same dose of Synthroid which would explain your situation.  Since you were doing so well on the Sandoz brand why not request it be special ordered into the pharmacy you use.  My pharmacy CVS orders in my Unithroid for me as they only stock one dosage.  To make it easy I have my doctor write a prescription for 100 pills at a time which is the entire bottle.

Your TSH is still very high at 2.5, though improving
Continue discussion
RSS Expert Activity
H1N1 and Our Pets
Nov 05 by Thomas Dock, Vet. Technician
In the ER: A Unicorn's Journey
Nov 03 by Jon Geller, D.V.M.
Doctors Resign Over Coca-Cola Fundi...
Nov 03 by Adam Tanase, D.C.