Wondering what the biopsy means

[th1269]

Hi Dr.

My biopsy results are unclear to me, could you translate for me please.

Present amidst a background of predominantly blood, it is only within one of the smears where ther is seen limited follicular epithelial sampling with no evidence of colloid apreciated.  A few small sheets of follicular epithelial cells appear bland and uniform.  A few other clusters of follicular epithelial cells, however, show pseudopapillary type architectecture with crowding of follicular epithelial cells, overlap of follicular epithelial cell nuclei and mild anisonucleosis with some nuclear irregularities.  Thus, as described, there is limited follicular epithelial sampling which precludes more definitive assessment; however, as noted, there are features present which prompt suspicion, and on the present sampling, the possibility of a neoplastic process such as papillary carcinoma cannot be excluded.  Thus, clinical correlation is required; consideration may be given to further evaluation, at a minimum; re-aspiration in an attempt to gain more cellularity for evaluation.
I am a 39 year old Mom and worried.
Thank you

[Mark Lupo, M.D.]

The specimen does not show many cells, but the cells present appear to have some suspicious features.  Would consider sending the slides to an expert (ie Dr Massoll at U Arkansas or Dr Baloch at U Penn) to see if a more definite diagnosis can be made on this sample, otherwise a repeat FNA may be necessary to see if this is suspicious enough to be removed surgically.