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Thyroid Cancer, Nodules & Hyperthyroidism (Expert Forum)
hyperthyroid//hypothyroid
Answered by
Mark Lupo, M.D. - Thyroid Nodules, Thyroid Cancer, hyperthyroidism, hypothyroidism, Thyroid Ultrasound
Thyroid & Endocrine Center of Florida
Sarasota - FL
Questions in the Thyroid forum are answered by Mark Lupo, MD. Topics covered include Goiter, Graves Disease, Hyperthyroid, Parathyroid/Calcium Problems, Thyroid Cancer, Thyroid Nodules/Cysts, Thyroiditis, Thyroid & Pregnancy, Thyroid Stimulating Hormone (TSH), Thyroid Tests, and Thyroid Surgery.
hyperthyroid//hypothyroid
by dhflp, Oct 21, 2006 12:00AM
TSH 0.371(0.400-5.500),T4 7.5(5-11), T3 85(94-170), T4 Uptake 0.86(0.70-1.20), FTI 8.8(6-11). CBC and CMP are all normal in this middle age male. 1. What's his thyroid function called? 2.Do above thyroid function tests results suggest hypothyroid is more likely than hyperthyroid or it's other way around? 3.Usually what causes TSH to be between 0.2-1.0 (normal >0.4) most of the time,but at the same time T4 to be normal all the time? 4. How accurate are thyroid function blood tests,especially T3 and TSH,for example is it usual case where T 3 is tested and reported to be normal but actually it is below normal limits?5.Usually is thyroid antibody blood test positive or negative when person has (A) small (0.0-1.0mm) thyroid benign nodule(s) (B) nodule(s) which are cancerous? 6. What's the smallest (thyroid nodule) size in mm that thyroid ultrasound can detect?7.What's considered normal thyroid ultrasound (0.0,0.5,1.0mm if they can measure it that precisely because of margin of error)interval change in 6 months (for a small thyroid nodules)?8.Doctor told me adults who had a small <3mm stable thyroid nodule(s) for last 10 years have lower risk of getting cancer than adults who do not have thyroid nodules(s) at all.Is there any truth to this?9. A friend on his first ultrasound was told to have small thyroid nodules,but on second ultrasound ordered by different doctor was told that he did not have any thyroid nodules but instead had normal parathyroid glands.Did anyone have similar experience?10. Is TSH between 1-2 in healthy middle age adults the best(optimal)?Thank you
Doctor's Answer
by Mark Lupo, M.D., Oct 21, 2006 12:00AM
, Oct 21, 2006 12:00AM
Lots of questions! The labs are likely normal for that male - may be a mild thyroid problem, would repeat the panel (with free instead of total T4 & T3) in about 4 weeks to determine the pattern. Small <3mm nodules that are stable are unlikely (but not never) cancer and I would not conclude any decreased risk compared to a person with no h/o nodules. Antibodies are useful - mostly to help determine cause of thyroid lab abnormalities. TSH around 1 is likely optimal.
