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Thyroid - cold nodule
Nuclear medicine showed a cold nodule on my left thyroid. FNA results: The sears show heavily blood stained smears with thick colloid and many sheets of benign follicular cells. Macrophages and occasional giant cells are also present in the background. No malignant cells.  Benign, Category 2
Do I need follow-up ultrasounds?  What do the macrophages and occasional giant cells indicate?
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1711789 tn?1361311607
Hi there!

Benign appearing cells do not typically rule out a follicular carcinoma though an FNAC is sensitive for other forms of thyroid cancer. With a cold nodule, the suspicion would need to be kept at high end and further diagnostic techniques may be required. I would suggest discussing further management plan with your treating doctor.
Hope this is helpful.

Take care!
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The macrophages and occasional igian cells ndicate inflammatory process-thyroiditis; Colloid indicates benign colloid nodule instead of neoplasm where colloid is not present.
This nodule can be evaluated with ultrasound for echostructure changes.
In addition, Afirma molecular test can be used over the specimen if in doubt.
If nodule has strong capsule and less than 2.5 cm in size PEI ablation may be attempted.
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