Just wondering something else...after you increase your synthroid (providing there aren't any underlying issues), how long do you have to be on a dose of medicine before you start to see signs of improvement? Also, I have been asking if anyone thinks it's a good idea to take B12 vitamins? Had TT and I'm not defecient in it, but I've read some posts where people think it's a good idea. If so, how much should you take? What would be the standard dose? I am taking 2,500 iu of VitD as I am defecient in that and also a multi vitamin. Thanks everyone!