Aa
A
A
Close
907968 tn?1292625804
Change from Synthroid to Levothyroxine
Started off taking 25mcg of Synthroid, then upped to 50mcg.  Starting Sunday (two days) I'll be taking 50mcg of Levothyroxine.  I'm not sure why the change other than price(?) or synthetic over natural(?)...?  A second question; are there any side effects I should know about from changing from one to the other drug?
Cancel
7 Answers
Page 1 of 1
Avatar universal
Levothyroxine is the generic form of Synthroid. Both are synthetic, so price is probably the deciding factor.

Many doctors don't like to use the generic because of concerns over variations in the amount of medication in them versus the stated amount.  Supposedly, the brand names are much more consistent.  However, whether this is true or Big Pharma just ran a very successful smear campaign against their competition is open to discussion.

The medication in both Synthroid and levo is the same.  Some people have problems with the fillers or binders the different brands and generic contain.  This is true between brand names as well as between brand and generic.

Have you been feeling well?  If so, it might not be worth it to rock the boat with any changes.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
907968 tn?1292625804
I probably should have mentioned this but didn't think about it till your question...  My voice changed.  I can't tell you how exactly because of an ear problem but I do know it was quieter and deeper.

  As a side note; I've just started to have this 4 year old ear problem taken care of a few days after my last PCP appointment.  This is unrelated to the change in medication.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
Voice changes are not unusual with hypo since an enlarged thyroid or thyroid nodules can press on the laryngeal nerve causing changes.  This often takes the form of hoarseness or raspiness.

Is that your only symptom?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
907968 tn?1292625804
related to the change in medication, yes.  Outside of that...
May 09, first blood test
Sept. 09, diagnosed with thyroid problems
Nov. 09, second blood test
Dec 09, Told numbers are better but still low. Doubled Synthroid till refill, then change of meds.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
But what I'm wondering is if you are still feeling any hypo symptoms other than the voice changes...fatigue, constipation, low HR and/or BP, etc.

Do you have the actual numbers from your December bloodwork and the reference ranges on FT3 and FT4?

My basic thought is that if most of your symptoms are gone and you are doing well on the Synthroid, it might not be time to rock the boat by making an unnecessary change to generic, especially since you have just increased your dose.  If you switch to generic, you will be throwing another variable into the mix, and you won't know if any changes are the result of the increase or the change in drugs.  I'm a firm believer in the scientific method...control all but one variable.

I think it might be helpful if you listed your hypo symptoms on diagnosis versus current symptoms.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
907968 tn?1292625804
You answered my original questions and I don't have any more symptoms.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Avatar universal
If you don't have any more symptoms, then I would seriously question doubling your dose, especially in light of your cardiac issues.  If your doctor feels your levels need to go up, then a very slight increae might be in order, but a 100% increase might send you right into hyper (fast).  We don't all do well at what our doctors think are the "ideal" levels.  If your symptoms are gone, why increase at all?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Submit Comment
Your Answer
Avatar universal
Answer
Know how to answer? Tap here to leave your answer...
Answer
Submit Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Thyroid Disorders Community Resources
RSS Expert Activity
233488 tn?1310696703
Blank
Marathon Running Done Over Many Yea...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
233488 tn?1310696703
Blank
New Article on Multifocal IOL vs &q...
05/15 by John C Hagan III, MD, FACS, FAAOBlank
748543 tn?1463449675
Blank
TMJ/TMJ The Connection Between Teet...
01/15 by Hamidreza Nassery , DMD, FICOI, FAGD, FICCMOBlank
Top Thyroid Answerers
Avatar m tn
Blank
gimel
MI
Avatar f tn
Blank
goolarra
Sisters, OR
649848 tn?1424570775
Blank
Barb135
FL
Avatar m tn
Blank
flyingfool
WI
657231 tn?1453836403
Blank
rumpled
Northern, NJ
Avatar m tn
Blank
des900
Calicut, India