Have you had an ultrasound test of your thyroid gland?
You might find this interesting also. In the words of a good thyroid doctor, "The free T3 is not as helpful in untreated persons as the free T4 because in the light of a rather low FT4 the body will convert more T4 to T3 to maintain thyroid effect as well as is possible. So the person with a rather low FT4 and high-in-range FT3 may still be hypothyroid. However, if the FT4 is below 1.3 and the FT3 is also rather low, say below 3.4 (range 2 to 4.4 at LabCorp) then its likely that hypothyroidism is the cause of a person's symptoms."
I think you need a good thyroid doctor.
He says that the combination of my blood work anomalies and symptoms don't correlate with a thyroid issue, I'm feeling very dejected here that they are struggling to solve my health issue
I just noticed that you have several other threads with more information. That is what happens when you start a number of different threads. Too much opportunity for info to be overlooked.
Anyway, now that I know about the Hashi's, which was one of my questions, that explains some of what you are going through. Hashi's nodules can leak thyroid hormone faster than normal, at times and cause swings from hyper to hypo and back.
In the other thread it seemed that there were two options mentioned. One is called "block and replace" and the other was a TT. In view of that I am puzzled that the Mayo doctor thought you had some type of non thyroid issue going and and was going to test you for a pituitary tumor. What brought him to that conclusion?
Hypo cold in the mornings,sometimes fatigue but not often, light headed
Hyper tremors, anxiety, night sweats, hot in the afternoons and night, weight loss
To me your test results are far from what most of us find we need to prevent hypo symptoms. Even though results fall within the so-called "normal" ranges, the ranges are far too broad to be functional across their entire breadth for many people. Optimal levels for many people are more like the middle of the range for FT4, at minimum and the upper third of the range for Free T3, or as necessary to relieve symptoms. Symptom relief should be all important, not just test results.
In addition, there are other factors that can affect how thyroid hormone is transported and utilized by cells in your body. some of those are Vitamin D, ferritin, and cortisol levels.
With your high TSH, was there any consideration of Hashi's? And last for now, please tell us about your hypo symptoms. Also tell us about your hyper symptoms.