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Florinef & Depression???
Hi,

I'm new to the forum. I'm here about my mother, who is a patient of Hypothyroidism (for abt 10 yrs) and Addison's for a good number. Things were under control, till about 8 months ago, her Na levels suddenly dropped and she was later diagonosed with 'Postural Hypotension'. She had to consume 2-3 litres of salt water to keep up her Na levels and her postural imbalance remained.

About 2 months ago, we came across Florinef and she was started on it - 1 mcg, upped to 2 mcg - her BP levels shot up, then brought down to 1 mcg.  

Her postural imbalance went away, but then she was also on 'Eptoine' for a suspected fits problem. This however was stopped, because they didn't find the problem. So we suspect her imbalance at that point could have been because of 'Eptoine' (known side-effect). Also, it is known to interfere with the effectiveness of 'Florinef (Fludricortisone)'.

The new problem - this began after abt 6 weeks of Florinef - Depression!! And it seems to get worse. We found a bunch of links linking Florinef with Depression. Has anyone else experienced this??? Here are a few links -
1/ http://home. intekom.com/pharm/bm_ squib/florinef. html
2/ http://www.drugs.com/cdi/fludrocortisone.html
3/ http://www.pubmedcentral.nih.gov/articlerende r.fcgi?artid= 484603

I would be VERY VERY grateful for a response!! We will be consulting her doctor soon, who is a capable man, but has not seen many such cases.

Thanks so much for your time!

Warm rgds,
HS


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Avatar_universal
Has she had her blood tested lately for thyroid and adrenal levels?
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Yes ... they are regularly monitored and they came out ok (Cortisol was 'slightly' low). But we'll be having her tested again soon.
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