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Hashimoto ...

My daughter, now 19 years old was diagnosed with panhypopituitarism at the age of 4.
She has been treated all these years according to her needs... growth hormone, cortisone, thyroid hormone, progesterone , estrogen....
Also 5 years ago, she had an epileptic surgery. A few days ago that we visited the neurologist he sent her to make a test for Hashimoto. Even that it is not his side of medicine, he wanted to know for his records.
I haven't mentioned it to the Endocrinologist, since I think it he suspected of this it HE who should have cared for this test.
After I have read  the symptoms of Hashimoto, I find them very much in common with the one of panhypopituitarism.
What is the diference in treating each one ? Does one is born with Hashimoto, or aquired after ?
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231441 tn?1333892766
If she has panhypopituitary then her pituitary doesn't produce TSH (and TSH is a useless test for her).  Her thyroid should also be very small (as there is nothing to stimulate it).  Having antibodies or not to her thyroid will not make any difference as far as thyroid is concerned becuase her thyroid doesn't work anyway.  Unless the thyroid somehow develops nodules or growths.

The symptoms of hypothyroid are of course in common with panhypopituitary (as both have no/low thyroid function) and need to be replaced with thyroid hormone.

however, she has other hormones that also need to be replaced.

If she is properly medicated on all hormones, hopefully she feels well and doesn't have sypmptoms.
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649848 tn?1534633700
COMMUNITY LEADER
Yes, the treatment for Hashimoto's is the same as for hypothyroidism.  

Do you have the reference ranges for the FT3 and FT4?  I'd be interested in seeing where your daughters levels fall within the ranges.  
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Avatar universal
We will make the TGab, only she is tired of so many doctors and  blood test... sure in a couple of months she will need to make more and we will make them at that time.
Anyways, from what I understand, she still being treated for her unsufficent thyroid hormone, which is the treatment for Hashi ? Is that correct ? the same treatment ?
Tks !!!
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
In order to diagnose Hashimoto's for sure, she will also need a Thyroglobulin Antibodies (TGab) test.  

Both Thyroid Peroxidase Antibodies (TPOab) and TGab are used to diagnose Hashi's and she will need them both.  Some people have only TPOab, others have only TGab and still others have both.  Your daughter's TPOab, indicates that she does not have Hashi's, but it can't be ruled out without the TGab test.  Plus, sometimes, people actually *have* Hashi's, but haven't developed the antibodies yet.

Also, has she had an ultra sound to check for nodules on her thyroid?  Many with Hashi's have nodules and/or a swollen thyroid (goiter).  

What are the reference ranges for the FT3 and FT4?  Ranges vary from lab to lab (and country to country) so must come from her own lab report.  Please post the ranges, so we can see whether her levels fall within them, and if so, whether they are high or low in the ranges. This will make a difference in the way she feels.  
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Avatar universal
Her last Lab test are like this.
TSH - smaller that 0.03 mIU/l
Free Thyroxine (FT4) - 19.5
Triiodothyronine Free FT3 - 5.61
Thyroid Peroxidase Ab - smaller than 10 IU/ml

Well, even thought that she was diagnosed with panhypopituitarism, she has been also lacked of all the hormones in the body. So maybe that is why the neurologist actually wants to know if she has also Hashimoto's disease.
With this lab test is it possible to know if she suffers from Hashimoto's disease ? What other test should she make ?
Tks
Helpful - 0
649848 tn?1534633700
COMMUNITY LEADER
Panhypopituitarism is a lack of human growth hormone, which causes children to grow very slowly.  It's treated with injections of human growth hormone.

Hashimoto's is an autoimmune thyroid disease, in which the body see the thyroid as foreign and produces antibodies to attack and destroy it.  Hashimoto's, itself, has no treatment; however, as the antibodies destroy the thyroid, it produces less and less hormones, causing the patient to become hypothyroid.  In the end, it's the hypothyroidism that's treated with thyroid replacement hormones (not the same as human growth hormone).  

Do you have lab reports indicating which tests are being done on your daughter's thyroid, what the results are, along with the reference ranges, which vary from lab to lab, so must come from her own report.

Some people may be born with Hashimoto's; others acquire it later in life.  I was 58, when I was diagnosed, but suspect I'd had it for at least 20 yrs prior.
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