Help me

[sara000]

I was diagnosed with progressive ataxia in 2006.  I cannot walk independantly, I have severe tremors, difficulty talking, nystagmus, weakness on one side of my body (nondominate side). ... [More]

My problems started in 1998, I was diagnosed with Grave's disease in 1999.  At that time my only problem was a slight tremor in my left hand when doing something of motion.  My thyroid was destroyed by radiation pills and I was put on replacement pills.

My grandmother died of a heart attack after a stroke.  My mother had lupus plus shingles.  Thyroid problems runs throughout my family, though most of them had "hypo" problems, I'm the only one who had "hyper".

I'm wondering if my problems could be endocrine related.  I have had many tests done.  I'm negative on all of my hereditary ataxias, lupus, RA, Hashimoto disease, etc tests.  My CMP comprehensive metabolic test showed a slightly elevated blood calcium of 10.7.  Two following tests showed calcium levels of 9.5 and 9.8 (within normal range).  My PTH was 7 (low).  So I'm guessing that rules out a parathyroid tumors.  

I have my next appointment with my endocrinologist 3rd of September.  

I've been B12 and Vitamin E deficient, but both are within normal range and I'm continuing to get worse.  Can malabsorption problems be the culprit?  My blood tests for celiac disease and gluten intolerance are both normal.

Can you shed some light on this?

Thank you,

Sara

[thyroidian]

dear sara, i had graves disease in 199, 7, which went out of control,and medication was no good so i had a sub total thyroidectomy in 1998.to rectify the problem. in the june off 1998, i had problems with my walking nystagamus, and weakness more in the left side off my body, i was diagnosed with MS multiple sclerosis have you had any scans done? or a lumber puncture? and may i ask do you have any bladder problems? as i have a lot.  can i also ask have you had graves or is it hashimotos? as i have been reading a lot about hashimotos encethalopathy which gives neuro problems. i might be barking up the wrong tree. but you might have high titres off thyroid antibodies, and they are a marker for hashis encethalopathy? i dont think its heard of much in england but there are a few cases in USA.   they say that graves is an autoimmune disease so maybe look at autoimmune....... i hope this as been of some help, and maybe ive got it wrong but you sound like you might need a neurologist.          good luck keep me posted  thyroidian