Help on My Case Please

[Giga_2015]

Hi

Im 24 (M) year old.

I have hyperthyroidism for 2 months and i diagnosed before 1 month. I was given carbimazole (thyrocab tablets).
After 20 days i got hives which is not going ( today is 6th day ). I had CBC & TSH, T4, T3 Test. Doctor changed
medicine from carbimazole to PTU ( propylthiouracil ). Do you have any idea if its fine or not or anyone took PTU ?
Also please see my below result and let me know if you have any idea.

TSH - 0.007  TSH Normal Range - ( 0.27 - 4.2 ) ( before 1 month ago TSH was 0.02 )
T3    -   1.34     T3 Normal Range - ( 0.84 - 2.0 )
T4    -   8.02     T4 Normal Range - ( 5.1 - 14.0 )


Any help will be really appreciate.

[Giga_2015]

My new test results -

Thyroglobulin Antibodies - 728.1 - IU/ml - N:  115 IU/ml

Thyroid Peroxidase Antibodies -      8.78 -     IU/ml -   N: 34 IU/ml

Thyroglobulin (Tg) -0.25 -     ng/ml -    0.2-70 ng/ml

SGPT -         18 -  U/L        -     0-40 U/L
SGOT -         19 -  U/L        -    0-37 U/L
Total T3 -   1.42 - ng/ml      -   0.84-2.0 ng/ml
Total T4 -   3.32 - ug/dl      -    5.1-14.0 ug/dl
Free T3 -   4.95 - pg/ml    -   2.0-4.4 pg/ml
Free T4 -   0.58 - ng/dl      -   0.93-1.7 ng/dl
TSH -       20.64 - mlU/L    -   0.27-4.2 mlU/L

After last test, I took 3 PTU Pills for 6 days then only 1 for 24 days.

thyroglobulin antibodies are too much higher. So it confirms I have some autoimmune disorder right?

TPO is in level but I heard somewhere there are no Antibodies in blood in healthy person. Thyroglobulin is low so I do not have cancer right? any Idea what further test I should do? and what current dosage I should take? I still feel weakness.

thanks for the info :)

[Giga_2015]

Hi

Yes. Now im on dose 1-1-1. one medicine at morning, noon & night.
at this time my weakness also going slowly and tinnitus also sometimes so low or absent. rest things are normal.

only one thing im dealing at this time is im getting every 3-4 days reaction of PTU. my skin gets Up like lizards and down again ( https://s-media-cach...ec5dabe26c1.jpg  )  . it continues for 1-2 hours.

I went to dermatologist and with his medicine i had no issues in 10 days

[gimel]

From your lab test results it appears that your dosage of PTU was too high.  Was your dosage changed after the last set of test results?

Also, it would be much better if you can get the doctor to test for the biologically active thyroid hormones, Free T3 and Free T4, rather than Total T4 and Total T3.  

What symptoms do you have besides the tinnitus and the weakness?

[Giga_2015]

Update :

I got little tinnitus ( noise in mind/ear ) by doing shirshana so for now I left it. so if you getting it too then try to do it for only a few seconds.

I did lab test again. here are new results

Total T3 - 0.904  ( 0.84 - 2.0 )
Total T4 - 4.1 ( 5.1-14.0 )
TSH - 22.88  ( 0.27 - 4.2 )


Lever test

SGPT - 40  ( 0-40 )
SGOT - 29  (0-37)


Doc. said Free T3-T4 not necessary and my lever test are good. ( to me looks not much good but I trust doctor ) My dose of PTU was 2-0-2, now its 1-1-1.

Anyone have any idea if we get all these in normal range so howmuch time it takes to get it unbalanced again?

For now im good but still having weakness.

[Giga_2015]

As many of you  know thyroid issue can be because of pituitary gland issues too.
which is sending TSH.

So I got idea & tried doing Shirshasan :-
https://arhamyogalaya.files.wordpress.com/2009/12/img00582.jpg

for some days and I see changes in my mood and behavior. So I highly recommended it to all. because of shirshasan, our mind & eyes gets high amount of blood which can fix many issues.

If shirshasan not comfortable, you can also do adho mukha svanasana :-
http://www.theyogasanctuary.biz/ys/wp-content/uploads/2011/03/down-dog-jen.jpg

after 2-3 days if you feel so uncomfortable then should stop doing it.

also I suggest to do different kind of Yogas which helps to balance Hormones & gives
good feelings.

[Giga_2015]

Just found today I have increased skin pigmentation ( small white dots ) and I heard its due to this thyroid condition.

Do you think this can be reversed as current treatment continues?

[Giga_2015]

Thanks very much for your reply :)

from start i have no any major signs of hyperthyroidism.
Only i don't stay in mood, having little weakness. that's it. bowel issue comes & go.

Hope to get better once and for all bcoz i heard many can make them out of this in 6 month to 2 years.

[yankeeRN]

Hi--I also have hyperthyroidism (since Sept 2011). I had been on Methimazole but I developed hives after a month or so.  I was switched to PTU.  I think I had hives for a week or so after I had stopped the Methimazole since it can take a bit for the drug to  completely get out of the body. BUT there are some people who are also allergic to PTU. I have been on the PTU for almost 4 years (doses varying depending on my symptoms and labs)--no hives with this. As you probably know there is a "Black Box" warning on the PTU for potential major liver effects BUT my thoughts are that this is for high doses--so far so good for me--plus this is the safer drug for pregnant women with hyperthyroid so it makes me feel ok with it (though I am not pregnant--if it can be ok for mom and baby then it should be ok for me). I don't have a choice since I don't want the radioactive iodine or the thyroid removal. For the most part I feel good on PTU--have had some ups and downs necessitating dose adjustments.  Listen to your body-- if you feel off get lab work so meds can be adjusted if needed. Per your tsh it is still low but your FT3  and TT4 look ok  (could be a bit higher) BUT more importantly how do you feel?  What were your hyperthyroid symptoms and have they subsided?  Also since you have recently started on the anti-thyroid drug be watchful because you may reach a point where you become hypo and medication will need to be adjusted. Hypothyroid symptoms for me were scarey--I felt like the life had been sucked right out of me--I could barely function--I was also so depressed yet "felt no emotion"--I tell you this because IF you get there--- I want you to know there is hope and that they might just need to back off on the anti-thyroid med if you are hypo BUT you will feel better it just might take a month or so. You might never get hypo but no one ever warned me and I think it is good to know. Best wishes for good health. FYI this forum is wonderful---it helped me immensely when I was first diagnosed with hyperthyroidism (Grave's)--I still visit site to see if I can give back and help someone else.