High TSH, normal T3 and T$

[RonCorn]

I have been on Synthroid for 1 1/2 years for hypothyroidism.  Recently, my test results were normal, or slightly below normal, for T4 (.9) and T3 (229).  But my TSH was 43.9.  Six months ago my TSH was 1.35, and T4 was 1.44.  But, at that time I reduced by dosage of Synthroid because I was suffering from extreme insomnia, and was always highly alert and full of energy, all hyperthroid symptoms.  I was sure that Synthroid was causing this.

Could this TSH problem be a problem with my pituitary or hypothalamus, rather than my thyroid?  My doctor found no problems on Thyroid ultrasound and TPO antibodies test showed positive (high).

[gottama]

I don't think there would be a problem with the pituitary as you are more likely to get really low T4 with a really low TSH for this to be the case = secondary hypothyroidism. Although i'm not entirely sure. The TSH of 43.9 is your body saying that although the T4 is just low normal, it is not enough T4 for your body at this time. I live in UK and we use different units of measurement for T4 and T3, but i have had the equivalent of 0.7 for T4 with a TSH of 30 for one of my results which is fairly similar to your recent result. The high TSH is your bodies way of saying it needs more  

[gottama]

your probably right that the synthyroid was causing your hyperthyroid symptoms. How are you feeling now?

[stella5349]

I really feel that the Hypo is causing a problem. Your TSH - if this is recent? - is very high as you now and your T4 can not catch up as the post said above. I see your concern of your Hyper symptoms. Have you been on the same dose of meds all this time?   If I may ask - are you pretty faithful taking your meds everyday and around the same time?  I don't think you require a T3 addition to your Synthroid as of right now - due to the hyper symptoms you experience.

Post back later  with answer on these questions if you can.

[Jeanne526]

question if I have a high tsh but noraml t3 and t4  am I hypo or hyper
can't figure it out... and does anyone know if you start on medicine do you have take it for the rest of your life ???  ty

[stella5349]

High TSH levels will indicate Hypothyroidism. The higher the TSH - the more hypo

and vise versa with Hyperthyroidism.

Low tests indicate an over functioning gland called hyperthyroidism