High TSH (TSH > 150 ) is not Affecting Weight (46 kg)

[suketu]

My wife has been detected Hypothyroidism before 4 months.
But she was not having Any Symptoms. Her weight was 46kg
At that time TSH level was 123.
We started medications. Althroxine 100 mcg.
Withine three months of time TSH level reduced to 0.68.
From last month she was taling 50 mcg dose
Today test result is showing TSH more than 150.
Still her weight is 46 kg.
So Can you tell me the reason for not heaving symptoms of Hypothyroidism & too much fluctuation of TSH Level?

[mitchell1204]

One of the problems is it takes 4-6 weeks to adapt to the medication change. They shouldn't be jumping more than 25 mcg at a time. The balancing point is real fragile.

From what I'm seeing, symptoms tend to be worse the longer you go undiagnosed. Your body tends to adapt without. It's a long road down and it's a long road back up.

I went undiagnosed for 1-2 years. I had a few symptoms. I just thought it was my age creeping up on me. Then I was diagnosed and started Levothyroxin. It seems like most of the symptoms hit me like a rock then. I was expecting improvement but got worse.

My nurse was also diagnosed, 50 mcg and 6 weeks later she was back to normal. So I guess each person/case is different.

[chigirl29]

My levels changed a lot, and I am now hypothyroid and am on 100mcg of Levothyroxine.

Have her thyroid antibodies checked.  That could cause the gland to produce more at some times and less at others--making dosing adjustments difficult.

I waited until my immune system stopped attacking my thryoid gland; however, I had an extremely high level of hormones that dropped unbelievably fast.  The result put me in the hospital.

I have never had any problems with my weight.  I was mainly tired and had muscle pains and low grade fevers.  At first, I thought I had lupus, but then I discovered that the immune system can attack the thyroid gland through research.

I did lose a lot of weight when hyperthyroid, but I have had no problems since becoming hypothyroid.

[Venora Moonwind]

Weight gain doent necesarily happen but I amsure if you ask her about other things like dry skin and hair and joint aches blurry vision are to name a few. she was doing well on the 100mcg so why did sdhe reduce to 50mcg? If it were me I would keep taking the 100 mcg and keep my tsh down. you have to take it for life Its not like an antibiotic that you take till you feel better.
Love Venora