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How long does Armour Thyroid take to work?
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How long does Armour Thyroid take to work?

Having been suffering from an underactive thyroid for over 5 years (and suspected overactive for about 5 years before that), I finally found an Endocrinologist who did extensive tests and found that my thyroid levels are slightly under at tissue level. He prescribed me a 1/4 grain (15mg) Armour and I've been taking it for 6 weeks but feel worse than I did before! My tiredness, constipation, muscle aches, hair loss and other symptoms are all worse and I've started feeling a bit depressed. Is this normal and will I start feeling better or is Armour not for me? Any advice greatly appreciated as I can't find the info I'm looking for anywhere!
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Avatar_m_tn
T3 hormone has a half life of only about a day, so it only takes about a week for the levels to build up close to the max you will see from that dose.  The effect on symptoms tends to lag behind the med levels; however, I am surprised that you feel no effect after 6 weeks.   This prompts me to wonder if you are getting enough med to really have any significant effect, so we really need to see what your thyroid hormone levels look like.  Please post test results and their reference ranges, for whatever thyroid testing has been done for you.
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Avatar_n_tn
Thanks for the reply to my post Gimel! I'll get hold of the results and post them on here. I'm due to have more blood tests in a month and go back to the Endo so it will be interesting to see what the score is.
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Avatar_m_tn
If you are going back for testing, insist that they check for the actual, biologically active thyroid hormones, which are free T3 and free T4 (not to be confused with total T3 and total T4).  FT3 is the most important as it is four times as potent as FT4, and FT3 levels correlate best with hypo symptoms.  Symptom relief is what it is all about, not just getting test results to a level that the doctor thinks is okay.  In my opinion the very best way to treat a thyroid patient is to test and adjust FT3 and FT4 levels with whatever meds are required to alleviate symptoms.   The most difficult part is to find a doctor that is willing to treat your symptoms like this, instead of just going by TSH.  You might find this article interesting.

http://www.hormonerestoration.com/Thyroid.html
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Avatar_n_tn
I've just found some paperwork from my Endo which states that I have 'low serum free thyroxine and free tri-iodothyronine concentrations' - having looked these up on the net I see that these relate to the free T3 and T4 which is good news. I also found the blood test form for the blood work he wants me to have before going back to see him in about a month when my Armour is beginning to run out. It says nothing (as far as I'm aware) about thyroid tests but to test CRP, LPOA, APOA, APOB - all cholesterol from what I can gather (mine's high) and HOMO and MK6. /not sure what these are? It also doesn't state that I should fast which I know from much experience that if they're testing my cholesterol then I need to fast. Strange. Thanks for the info and web link - I'll have a good look at that.
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Avatar_m_tn
Just a couple of thoughts.  For most accurate results when taking a T3 type med, don't take your thyroid med on the morning of the blood draw.  It's good that you have been tested for FT3 and FRT4.  Those tests really show where you are with thyroid.  Suggest that you get a copy of the test results and reference ranges and post them here for member comment.

Additionally,the amount of medication you are on is quite small, but that is fine if the doctor plans to continue to increase enough to alleviate symptoms.  This is something you will need to find out about.  If he plans to medicate you based on TSH, or to just get your FT3 and FT4 up into the bottom end of their ranges, that may not do it for you.  After hearing of so many patients that had FT3 and FT4 levels within the low end of the ranges and being told nothing further was required, even though they continued to suffer from hypo symptoms, I did a whole lot of thinking about it and this is what I concluded.


The reason the reference range for TSH is called "normal", is that it's based on a large population of patients' test results.  From that data base the decision was made that about 2.5 % of people would  fall out of this "normal" range because they were possibly hypo or hyper.  From this decision limits were placed at plus and minus two standard deviations from the overall average and that was called the "normal" range, supposedly representing people who had no thyroid problems.  

After many years of bad experience with this "normal" range for TSH, they finally acknowledged 6 years ago that there were a lot more patients out there with hypo  and hyper problems than previously accepted when they originally used their data base to established the range.  
After excluding from the data base those patients who were suspect for hypo and hyper, they again analyzed the remaining data base and established limits that included 95% of the total data base and called these new limits "normal".  This changed the reference range from .5-5.0  down to .3-3.0, which is a huge change.  Unfortunately this change hasn't yet been accepted or acknowledged by most labs and doctors, even though the change was recommended by the AACE over 6 years ago.

Also, realize that the reference ranges for the "Frees" were established the same basic way.  These ranges have never been reexamined and modified like the range for TSH.  I am absolutely convinced that this is the reason why so many hypo people fall into the lower end of the ranges for FT3 and FT4 and are still told they are "normal", and nothing further is done.

In one my past lives I had a lot of training and experience in statistical analysis.  Based on that experience, if I had to estimate what a revised range for FT3 would be if the data base were purged of suspect hypo and hyper people, like was done for TSH, then I would say the FT3 range should change from 2.3-4.2 pg/dl up to about 3.2-4.3.  And FT4 probably would change from .60-1.50 ng/dl up to about 1.0-1.55. Quite a difference, huh?  Think maybe that is why we hear from so many people that have hypo symptoms, yet they are in the "normal" ranges for the "Frees"?  I'd bet my last dollar.    


Sorry to lay all this info on you, but I think you need to discuss all this with your doctor and determine if your doctor is willing to treat you by testing and adjusting FT3 and FT4 levels within their ranges,  as required to alleviate symptoms.   If the doctor has any problem with this, then you need to start looking for a good thyroid doctor that will do so.

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734073_tn?1278899925
It's probably the Armour brand not working well for you. They reformulated their product(changed the binders and fillers) Many people who had always done well on their product, suddenly began having hypo. symptoms and changes in blood work that were not for the better! Switch brands or have it compounded! We switched to Nature-throid (desiccated porcine) and doing so much better then we were on the "new Armour"  You also said that it was good that your free t3 and free t4 were in the low end. If my daughter' are in the low end of normal then she has sever hypo. symptoms, similar to those you've described. She does better when the freet3 and freet4 are kept on the high side of normal range with her TSH supressed to under 1. She is nine and born without a thyroid gland! Change your med and get that t3 and t4 up a bit and I bet you will feel better.
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Avatar_n_tn
Thank you both so much for your comments and help on this! I tried to post something yesterday but internet connection went! After reading the posts I decided enough was enough. I went for blood tests yesterday morning (having taken the last Armour the previous morning) and saw my Endo this afternoon. My results were as follows: (these are in different measurements to yours however and I can't figure out where on the web to convert them, sorry!)...

TSH - 1.21 mIU/L (normal range 0.27 - 4.20)
Free Thyroxine 13.3 pmol/L (normal range 12.0 - 22.0)
Free T3 -  3.8 pmol/L (normal range 4.0 - 6.8)

As you can see, the T3 is under and the T4 is only just above the 'normal' range. I told my Endo what you said about Armour's reformulation and he was really interested and said he wasn't aware of it - he was very glad I'd told him! Consequently he has switched me to a 1/4 grain of Nature Thyroid a day. He said it should start working within a few days and definitely within 2-3 weeks and if I'm not feeling better in this time then to increase it 1/2 a grain and to go back if there are any problems. If not, I am to just see him in the New Year having had my blood work done again so he can see how my levels are. I imagine I may need to go higher than 1/2 a grain judging from what I've read here and on other websites, so we'll have to see!

Already, having now missed two doses of Armour I feel loads better. Yesterday I really struggled and couldn't see how I was going to make it through the day, let alone the week but I'm feeling so much more positive about everything and I have you to thank gimel and magpieannie, thank you so much! I'm also so lucky to have found an Endo who really knows his stuff and listens. I can't believe how many Doctors I've visited and blood tests have been done for my thyroid function over the past 10 years and only now has this been discovered after years of feeling unwell. (Well, actually I can believe it because exactly the same happened to my Mum). I will report back once I've started taking the Nature Thyroid, fingers crossed!
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734073_tn?1278899925
Okay, this is great! You are very welcome for the help. Gimel's advice on the ranges is right on. She helped me lots when I was left in the dark, so a BIG THANKS also from me to Gimel. I say, we are all in this together and thank God for the computer and this site! Now, just so you'll know, it took a whole grain more of the Naturethroid then the Armour for my daughter to feel right.(the conversion chart seemed a little too modest) She was on 120 mg of Armour , but she is on 190 mg of Naturethroid to feel the same as she did on the good (old) Armour.. The chart says that 60mg Armour (1grain) = 65mg Naturethroid (1 grain) It also took her several months on this optimal dose to get rid of most of the hypo. symptoms that she developed on the reformulated Armour. We upped it every 10 to 14 days by 1/2 a grain until she came out of it.( The Hypo.Funk!). You need to really pay attention to how you are feeling (symptoms) and remember "gradual increases over time") On the blood work, test in 8 weeks when you feel like you have been on the right dose symptomatically for a while. You want that freet4 and freet3 to line up closely at mid to high normal.TSH is not a factor really, and it will and should be low normal. Also, I like to put my daughters ranges on their own bell shaped curve with the reference numbers at either end. Then chat the actual lab result on their bell. The freet4 and freet3 should both be on the right side of the bell with bthe TSH on the far left. This gives a good visual and helps with seeing where you are at. A good book for you to read now is "Overcoming Thyroid Disorders" Dr. David Brownstein on Amazon. com. It's an easy read and it helped me so much! Keep us updated on your progress!
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Avatar_n_tn
Hello again!
I've now been on Nature Thyroid for about 6 weeks. After a couple of weeks on a 1/4 grain a day I have increased it to 1/2 a grain a day (taking 1/4 in the morning and 1/4 in the evening). Since increasing the dose I have started to feel a little warmer and find my body can warm up a bit more easily without using a hot water bottle etc which is great but I still feel like I have a long way to go as I'm still loads colder than everyone else! In addition, my hypoglycemic shakes seem to have lessened a bit but I'm still very constipated and my periods are still very irregular. (I had to wait 7 weeks for my last one).

I had my blood tested a few days ago with the following results:
TSH - 0.47mIU/L (normal range 0.27 - 4.20)
Free Thyroxine 14 pmol/L (normal range 12.0 - 22.0)
Free T3 - 4.4 pmol/L (normal range 4.0 - 6.8)
My Endo said this was a beautiful result and he was very pleased but I told him I still wasn't feeling great and that I'm still tired and really cold etc and as you can see, they are still very much in the low part of the range. Unfortunately he told me he doesn't want to increase my meds because my TSH will drop too low (because the medication is doing the job of the TSH, so the level has therefore dropped) and a low TSH is associated with osteoperosis. I was gutted but he told me that he will let me take a whole grain a day for a couple of weeks to see if I feel better and if I do, he can do a bone scan to see if my bones are good enough to endure the possible risk of osteoperosis. If they're okay then great, but if not then I'm not sure what will happen. I didn't realise it would be so complicated! I'm sure I will feel better on a grain a day but I just hope everything else falls into place as I can't live like this! The only thing now is that nowhere has any Nature Thyroid and although I've been told I could get Erfa as an alternative, my Endo is away until mid Jan, so I'll have to wait unfortunately but still, I'm getting there slowly! Has anyone else had anything similar with low TSH problems?

In addition, one thing he originally tested me for was glandular fever which I tested positive for (in that at some point in my life I've had it). We only briefly spoke about this result on the phone but when I saw him the other day, he told me that not only had I tested positive for it but I still have the antibodies from the infection in my system which means I haven't recovered from it yet and this is likely why I'm still tired, not necessarily because of my underactive thyroid. I'm certain I had it 11 years ago not long after I had my appendix removed and I also think I had it when I was about 16, although I had my tonsils removed and felt a lot better for about a year or so until I had to have my appendix removed. At least I know what has caused my fatigue and tiredness over the years now, even if there's nothing I can do about it. I have started researching the condition on the net however and it's very interesting what people have said - it's like they're describing me! I do wonder if all these things could be linked and possibly caused a chain reaction in some way.
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Avatar_m_tn
I have just been prescribed armor thyroid and I really hope it works! I have been sick for 5-6 years vomiting tired weak achy my TSH was 58.6 my antibody test was 2561. I'm so excited to try armor thyroid I have only taken it 2 days! I am without a gallbladder bc (it didn't work properly) without a uterus(bcd had terrible periods) and a cholesterol level of 120! So frustrating and not to mention the anxiety attacks and arthritis in my spine
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Avatar_m_tn
You've attached your post to a very old thread.  You will get lots more notice and response if you will click on the orange Post a Question button at top of page and re-post your message.  
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Avatar_m_tn
I'm just now reading this. Might be dealing with some Thyroid issues myself. Did the Armour help?  My doc prescribed it but I'm nervous that my Thyroid will forever be shot after taking the stuff. Will you have to take it for life?
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Avatar_m_tn
Magpieannie has not been active on the Forum for some time, so I don't think you can expect a response from there.  

Armour will not cause damage to your thyroid gland.  Armour or other meds containing T3 help when the hypo patient taking T4 finds that the body is not adequately converting the T4 to T3.  Since Free T3 largely regulates metabolism and many other body functions, it needs to be adjusted high enough in its range to relieve symptoms.  Many of our members say that symptom relief required that Free T3 was adjusted into the upper third of its range and Free T4 adjusted to around the middle of its range.  If you will please post your thyroid test results and reference ranges shown on the lab report, then we can help assess your status better.  

As to whether or not you need to be taking any thyroid meds, it depends on the cause for your hypothyroidism (assumed).  Have you been diagnosed as having Hashimoto's Thyroiditis, which is the main cause of diagnosed hypothyroidism?  If so, then you will have to take thyroid meds in gradually increasing amounts as necessary to relieve symptoms.  If you are one of the infrequent cases of a temporary hypothyroidism, then obviously you would not need to take it forever.  
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Avatar_f_tn
I agree with you 100%!  I have a great D.O. that I work with who has diagnosed me with Hypothyroid.  I'm on the slim side so no one would believe me when I kept insisting something was wrong with my thyroid.  Hair falling out, crispy hair, dark circles under eyes, low energy, very dry skin..My hair and skin have almost no sebum.  I suspect when I was in my teens that I had an overactive thryoid even though my doctor at the time said I was fine. My TSH is 3.7 and my T3 is 2.7.  I forgot what my T4 is.  My D.O. said that my TSH should be lower and that he wanted my T3 to come up closer to the 4 level instead of 2/7 which means the upper level I guess.  He prescribed me 1 grain of Armour each morning to start with until my next blood work.  My D.O. had stated all of what you are talking about concerning what's "normal".  How do these doctors just take lab work and base it on a whole bunch of people who may or may not be healthy????  This has been such a long journey and it's tiring.  The 1st doctor I saw when I strongly suspected thyroid and couldn't let it go, insisted that my TSH was in the normal range.  I also take biohormones started a year and a half ago for a surgical hysterectomy that I had 4 years ago in which my D.O. has been helping me with as well.  I am only 33 years old but all these other doctors wanted to toss me by the way-side and say that I'm menopausal so all of my symptoms are normal!  Really???  Just because I had a hysterectomy, I'm expected to be old on the inside and soon on the outside??   I feel that people are just some huge experiments with doctors not really caring what the consequences are.  I probably should have not even had a hysterectomy considering that had doctors listened to me and properly looked after my well being.  Too many cookie cutter doctors out there who shouldn't be doing what they are unless they have a passion, wisdom and discernment for their occupation.
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Avatar_f_tn
Hi, Can you help me?
I was prescribed Armour 15mg and feel no better, naseous all the time.
My doctor is basing this in the TRH test, my results were 23.02

My doctor it checking my levels after 8 weks of drug, and then I see her the following week.  Is this long to wait?

Thanks
Jackie
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Avatar_m_tn
Will be glad to help any way I can.  First, would you please click on the orange Post A Question button at top of page and re-post this.  Rather than attaching to this very old thread,  starting a new thread under your own name will get more notice and response.  

While doing that, please also post all your thyroid related test results, along with reference ranges shown on the lab report.  Also, do you have any symptoms other than nausea?  
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Avatar_f_tn
Ok, thanks, I just reposted it and added the information you requested
Thanks
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Avatar_m_tn
hi the best solution i was lack to find out was 2 present of t3  and 98 present t4  but it hard to get it because armour comes 20 present t3 and 80m present t4 so start with 15 milgram aramor add t4 25 mil to 50 mil sinthroid   with in 8 weeks  and if you still fell bad but your hart is not giving you chest pain   you can take maca root 500 mil to 1000 mil aevery other day maca is natual hormone stimulant  it will activate all you main hormones remember dont take more then 2mil of t3 you can lower you sinthroid med by moving to maca slowly or if you fell ok dont touch it . when the winter comes remember to increase you t4 because of cold weather your body work harder to make  hormones most important run on trad mill 15 a day everyday but watch your hart bit  
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