Thyroid Disorders Community
How much can topical cortisteroids affect thyroid labs?
About This Community:

This patient support community is for discussions relating to thyroid issues, goiter, Graves disease, Hashimoto's Thyroiditis, Human Growth Hormone (HGH), hyperthyroid, hypothyroid, metabolism, parathyroid, pituitary gland, thyroiditis, and thyroid Stimulating Hormone (TSH).

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

How much can topical cortisteroids affect thyroid labs?

Currently taking Halobetasol, Hydrocortisone-Iodoquil, and over-the-counter Hydrocortisone for psoriasis.

How much can these meds affect my thyroid labs?
___________________________________________________
My labs:
DEC 2011:
TSH: 1.4 UIU/ML (range of 0.3-5.1)

DEC 2012:
TSH: 0.7 UIU/ML (range of 0.3-5.1)

FEB 2013:
Ultrasensitive TSH:1.148 UIU/ML (range of 0.300-5.100)
Free T4: 1.02 NG/DL (range of 0.73-1.95)
Thyroidine Peroxidase AB: (HIGH) 45.0 IU/ML (range of <35.0)

Also, I had imaging done and I have been diagnosed with multinodular goiter (4 nodules).
2 Comments Post a Comment
Blank
1756321_tn?1377771734
TSH can be falsely decreased by medications including dexamethasone and corticosteroids.  When possible, discontinue medications for several days or more prior to testing thyroid levels. Ideally, measure TSH in the morning (between 8 and 9am) and fast overnight (TSH levels are affected eating food high in fiber).    

The researchers of the study "Clinical Significance of TSH Circadian Variability in Patients with Hypothyroidism" (Sviridonova MA, et. al.) found an average morning TSH level in the subclinically hypothyroid group was 5.83 mU/L and in the afternoon was 3.79 mU/L; 73% TSH circadian variability. Morning (8 - 9am), Afternoon (2 - 4pm).

Blank
Avatar_m_tn
In addition, I wanted to point out that TSH is a pituitary hormone that is totally inadequate as the primary diagnostic for thyroid issues.   At best TSH is an indicator, to be considered along with more important indicators such as symptoms, and also levels of the biologically active thyroid hormones, Free T3 and Free T4 (not the same as Total T3 and T4).

A good thyroid doctor will treat a hypo patient clinically by testing and adjusting Free T3 and Free T4 as necessary to relieve symptoms, without being constrained by resultant TSH levels.  You can get some good insight into clinical treatment from this letter written by a good thyroid doctor for patients that he sometimes consults with after initial tests and evaluation.  The letter is then sent to the participating doctor of the patient to help guide treatment.  In the letter, please note the statement, "the ultimate
criterion for dose adjustment must always be the clinical response of the patient."

http://hormonerestoration.com/files/ThyroidPMD.pdf
Blank
Post a Comment
To
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Thyroid Disorders Community Resources
RSS Expert Activity
469720_tn?1388149949
Blank
Abdominal Aortic Aneurysm-treatable... Blank
Oct 04 by Lee Kirksey, MDBlank
242532_tn?1269553979
Blank
The 3 Essentials to Ending Emotiona...
Sep 18 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Control Emotional Eating with this ...
Sep 04 by Roger Gould, M.D.Blank
Top Thyroid Answerers
Avatar_f_tn
Blank
goolarra
Sisters, OR
649848_tn?1357751184
Blank
Barb135
FL
Avatar_m_tn
Blank
gimel
MI
657231_tn?1390151580
Blank
rumpled
Northern, NJ
168348_tn?1379360675
Blank
ChitChatNine
1756321_tn?1377771734
Blank
Red_Star
Queensland, Australia