Aa
A
A
Close
Avatar universal
Hyperaldosteronism?
I went to mt Endo today to follow up on blood work she did because of episodes of high blood pressure
plus headaches, fatigue, numbness, thirst . . .

I sat for 10 minutes before sitting blood draw.
Aldosterone, serum   14.1  ng/dL
Renin Activity            0.4  ngmLhr
Vitamin D, 25 OH      28.4  ng/mL  (range 30 - 60)

previous results from blood work earlier this year:
Potassium     3.3   3.7   3.7   4.1   meq/L  (range 3.5 - 5.3)

She said that if Renin were non-existant and Aldosterone over 15, she would do further testing. Since I already take Vit. D supplements, she recommended more sunshine.

I have seen several references to the Aldosterone/PRA Ratio (she did not mention this). Mine would be 35.25.  ARUP Lab says "greater than 25 is suggestive of hyperaldosteronism" and Quest says >18.2 is Primary Hyperaldosteronism.

Any advice?
Cancel
6 Answers
Page 1 of 1
523918 tn?1244553431
Have you also tested for calcium? and the presence of cathecolamines in urine?, do you take diuretics? How is your thyroid? (TSH)?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
Calcium  8.8,  9.1  9.5  (8.5 - 10.1)
urine nd plasma catecholamines are low
plasmafree metanephrinesare ok
no diuretics
TSH        .7,   1.3
T3 free    2.7    --
T4 free   .94,   .99
Thyroid has multiple hurthle cell adenomas (benign)
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
523918 tn?1244553431
So you did all the tests, about the Aldosterone/PRA Ratio , she didn't mention but she did, an Aldosterone/PRA Ratio over 30 with ALDOSTERONE  higher then 15 ng/dL is suggestive of primary hyperaldosteronism. Further tests are required if aldosterone gets higher then 15. Those further tests include a non suppression of plasmatic aldosterone after administration of 500 mL/ h of fisiologic serum x 4 hours, and other tests (that doctors inject something). After those tests  (if suggestive )they will ask for  a high resolution CT scan for the suprarenal glands.
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
So with an Aldosterone/PRA ratio of 35.5 and Aldosterone of 14.1,
is there a possible adrenal problem? My Endo is not planning any further testing.

My Cortisol is slightly high and Autonomic Nervous System tests areslightly abnormal.

Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
523918 tn?1244553431
I think he is waiting to see if aldosterone gets higher then 15, then he probablyl request further tests....,  I've noticed you have asked Dr. Lupo, just wait for he's advice (I'll be waiting too), sometimes we think a value is high but for doctors  that value isn't high enough for a diagnosis  or aren't high enought to justify further analyses ( that sometimes are invasive). About cortisol, have you tested for ACTH?
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Avatar universal
My blood pressure is not always elevated, but when it is it lasts for a few days.
Maybe we should re-check then?

ACTH is ok.

I hope Dr Lupo responds . . .

Thank you,
P
Comment
Cancel
Comment
Avatar universal
Comment
Comment
Comment
Post Comment
Your Answer
Avatar universal
Answer
Do you know how to answer? Tap here to leave your answer...
Answer
Answer
Post Answer
A
A
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Thyroid Disorders Community Resources
Top Thyroid Answerers
649848 tn?1474485941
Blank
Barb135
FL
Avatar m tn
Blank
gimel
MI
Avatar f tn
Blank
goolarra
Sisters, OR
Avatar m tn
Blank
flyingfool
WI
657231 tn?1453836403
Blank
rumpled
Northern, NJ
Avatar m tn
Blank
des900
Calicut, India