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Hyperparathyroidism?
Hello! I am 34 (almost 35). Last year, right before I turned 34 I was diagnosed with a very rare, staghorn, kidney stone. Because it was so big, they had to do 2 surgeries. I keep showing white blood cells in my urine, but the cultures come back negative. I have already developed a new stone, though a small one. My surgery was just 6 months ago.   I'm in the process of getting my blood work from all my doctors, because I think I have hyperparathyroidism. Because my Parathyroid level was low last week (10.0) my doctor's say I can't have it. My calcium was 9.8 and my ionized calcium was 5.55. I was not fasting on any of this blood work. I have almost every symptom of this. I know in August, my serum calcium was 9.2, June 8 (2 weeks before my surgery) my calcium was 7.9. My kidney stone was 100% calcium deposit stone. I have been on parathyroid.com non stop, and I firmly believe I have this.  But, can anybody offer me advice?? I read this is deadly if left untreated, and I have 4 boys...I want to find out for sure if I have this. PLEASE SOMEBODY HELP!
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1756321 tn?1377771734
One study concludes the diagnosis of primary hyperparathyroidism should be pursued despite suppressed or low-normal serum intact PTH levels after carefully excluding other causes of hypercalcaemia.  "Very low or undetectable intact parathyroid hormone levels in patients with surgically verified parathyroid adenomas." PMID: 18284640.

Causes of hypercalcaemia:

Most common (malignancy and primary hyperparathyroidism account for 90% of hypercalcemic patients):

* Primary hyperparathyroidism

* Malignant disease:
- PTH-related protein (carcinoma of lung, esophagus, head and neck,
renal cell, breast, ovary, and bladder)
- Ectopic production of 1,25-dihydroxyvitamin D (lymphoma)
- Lytic bone metastases (multiple myeloma, hematologic
malignancies and breast carcinoma)
- Other factor(s) produced locally or ectopically

Uncommon:

* Endocrine disorders:
- Thyrotoxicosis

* Granulomatous diseases:
- Sarcoidosis
- HIV

* Drug-induced:
- Vitamin D
- Thiazide diuretics
- Lithium
- Estrogens and antiestrogens
- Androgens (breast cancer therapy)
- Aminophylline
- Vitamin A
- Aluminum intoxication (in chronic renal failure)

* Miscellaneous:
- Immobilization
- Renal failure (acute and chronic)
- Total parenteral nutrition

Rare:

* Endocrine disorders:
- Pheochromocytoma
- Vasoactive intestinal polypeptide-producing tumour
- Familial hypocalciuric hypercalcemia

* Granulomatous diseases:
- Tuberculosis
- Histoplasmosis
- Coccidioidomycosis
- Leprosy

* Miscellaneous:
- Milk-alkali syndrome
- Hypophosphatasia
- William’s syndrome
- Rhabdomyolysis (presentation is usually preceded by a hypocalcemic
state)
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