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I.V. Pulse Therapy Methyprednisone

I found an article online of a study done in Italy where (and I'm going off a foggy memory) where they performed IV Methylprednisone (pulse therapy) for 3-5 weeks and over 87% showed significant long-term improvement.  There was only 25 patients in that study, but, I am a 42 year old male diagnosed when I was 24 and I still have the inflammation around the eye lids and some minor proptosis.  Health and nutrition is excellent, I'd like to "get back to normal".  When I was in the hospital 1.5 years ago with acute pericarditis, they gave me LOTS of prednisone and guess what, for the first time since I was 21, my eyes looked "miraculously cured".  I want those results! :)  Surgery scares me and it's frustrating that such an immediate solution with immediate results is with a dangerous med.  Anyway, can IV pulse therapy result in stable long-term resolution?

Secondly, there is a wave internet interest in "mycoplasma" as the culprit of Graves Disease and a suggestion that antibiotics, long term to kill the mycoplasma (if one has it) will "cure" graves disease.  With an open clinical mind, can you share your thoughts?

Thanks
Jeff
Tampa, FL
4 Responses
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158939 tn?1274915197
Ummmmmm - methylpredisone (or methylprednisolone) is an antiinflammatory corticosteroids and is used to temporarily reduce swelling.  Long term use of corticosteroids can have detrimental effects to the neurological system, the immune system, electrolyte imbalances, heart failure, musculoskeletal problems, etc.

here's a link to the therapy:

http://www.****%20SODIUM%20SUCCINATE%20FOR%20INJECTION%20USP.html

Here's a few excerpts from the a warning at the end of the link:  

Manufacturers' Warnings In Clinical States: Glucocorticoid-induced suppression of HPA (Hypothalamic-Pituitary-Adrenal) function is dependent on dose and duration of treatment. Recovery occurs gradually as the steroid dose is reduced and withdrawn. Suppression persists for a period of time after withdrawal depending on dose and length of treatment time.

All corticosteroids increase calcium excretion.

Glucocorticoids may alter laboratory or radiological tests for serum T3 or serum protein-bound iodine, may decrease T4 minimally or decrease the uptake of 31odine.



Personally I don't think I'll be signing up any time soon but, hey, to each his/her own.
Helpful - 0
314892 tn?1264623903
I would doubt this theory without seeing a minstream medical publication suggesting it as a possibility.

I did a search and only came up with dubious websites.

Mycoplasma is a common cause of walking pneumonia and can cause a particular STD. It can also sometimes infect the heart or brain. I haven't read where it can infect the thyroid.
Helpful - 0
398849 tn?1210135972
would love to read them as well please supply us with links...
Helpful - 0
393685 tn?1425812522
maybe post your links you are reading
Helpful - 0
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649848 tn?1534633700
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Queensland, Australia
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