Aa
Aa
A
A
A
Close
Avatar universal

Is a 3,075 TPO unusual

I have had hypothyroid for 10 years.  (taking Synthroid 0.1 mg.) Just diagnosed with Hashimoto's base on the following tests. I was told there is nothing needed to be done at this time. (still suffering from typical hypo symptoms)

I have read many, many Hashimoto's forum posts and rarely see a TPO this high.  Should I be worried this is more than Hashi's or that it is progressing faster than normal...or what other issues could I be looking at?  I can't get in to see a specialist for over a month. yikes.

TPO:  3,075  (range <35)
Total T3:  83  (range 87-167)
Free T4:  1.07  (range 0.8-1.80)
TSH:  3.85  (range 0.34-4.82)

Thank you for your time.
Best Answer
649848 tn?1534633700
COMMUNITY LEADER
It's not unusual to have a really high TPOab; we've seen them higher than yours before.  The actual number doesn't really matter.  What counts is that you have Hashimoto's.  The antibodies aren't what are causing your symptoms.  Too low thyroid levels are causing those.

Your TSH is too high, even though the range goes up to 4.82.  Over 10 yrs ago, AACE recommended that the reference range for TSH be lowered to 0.3-3.0.  Labs (therefore doctors) have been slow (to put it mildly) to react.

Additionally, your doctor is testing total T3, rather than Free T3, which is the actual hormone used by individual cells.  Even at that, your Total T3 isn't even in range.  Along with that, your FT4 is so low in the range, I can see why you have symptoms. I'm finding it hard to trust your doctor when s/he says nothing needs to be done at this time.  Apparently, s/he isn't a good thyroid doctor.

Looks like you could benefit from an increase in dosage and maybe even the addition of a T3 med, but without a Free T3 test, we can't know that.  With your FT4 as low as it is, there just may not be enough to convert well.
3 Responses
Sort by: Helpful Oldest Newest
649848 tn?1534633700
COMMUNITY LEADER
It's pretty obvious that your doctor is placing too much reliance on your TSH and not even looking at how low the FT4 is, in its range.  Testing TT3 instead of FT3 is a dead give away that she's not thyroid savvy.  

I'd recommend that you try to find a different doctor, unless you think you can get this one to test FT3 and FT4, as well as TSH and pay more attention to your symptoms.  Some doctors are willing to be "educated"; others are so arrogant that they get upset when they find out their patients have been researching and will no longer follow them blindly.
Helpful - 0
Avatar universal
Thank you very much fro you information.  I definitely feel lost in this realm and kick myself for listening to her advice for the last 10 years stating being in the range is ok and only testing TSH till this month.

It is a relief to now have an idea where to start. Thank you very much!
Helpful - 0
Have an Answer?

You are reading content posted in the Thyroid Disorders Community

Top Thyroid Answerers
649848 tn?1534633700
FL
Avatar universal
MI
1756321 tn?1547095325
Queensland, Australia
Learn About Top Answerers
Didn't find the answer you were looking for?
Ask a question
Popular Resources
We tapped the CDC for information on what you need to know about radiation exposure
Endocrinologist Mark Lupo, MD, answers 10 questions about thyroid disorders and how to treat them
A list of national and international resources and hotlines to help connect you to needed health and medical services.
Herpes sores blister, then burst, scab and heal.
Herpes spreads by oral, vaginal and anal sex.
STIs are the most common cause of genital sores.